Comparative GO Graph (mouse, human)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BCLAF1
  • Mouse genes Bclaf1
  • Rat genes
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bclaf1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	BCLAF1	IDA		Human	PMID:10330179
Molecular Function	GO:0005515	protein binding	BCLAF1	IPI	UniProtKB:P10415	Human	PMID:10837489
Molecular Function	GO:0005515	protein binding	BCLAF1	IPI	UniProtKB:Q07817	Human	PMID:10837489
Molecular Function	GO:0005515	protein binding	BCLAF1	IPI	UniProtKB:P50402	Human	PMID:15009215
Molecular Function	GO:0005515	protein binding	BCLAF1	IPI	UniProtKB:P10415	Human	PMID:23541952
Molecular Function	GO:0005515	protein binding	Bclaf1	IPI	PR:P15209	Mouse	PMID:11591653
Molecular Function	GO:0003723	RNA binding	BCLAF1	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	BCLAF1	HDA		Human	PMID:22681889
Cellular Component	GO:0016607	nuclear speck	BCLAF1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	BCLAF1	IDA		Human	PMID:24100041
Cellular Component	GO:0005654	nucleoplasm	BCLAF1	IDA		Human	PMID:24100041
Cellular Component	GO:0005634	nucleus	BCLAF1	IDA		Human	PMID:10330179
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	Bclaf1	IEP		Mouse	PMID:20439489
Biological Process	GO:0006974	DNA damage response	BCLAF1	IMP		Human	PMID:17938203
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	BCLAF1	IDA		Human	PMID:10330179
Biological Process	GO:0043065	positive regulation of apoptotic process	BCLAF1	IDA		Human	PMID:10330179
Biological Process	GO:2000144	positive regulation of DNA-templated transcription initiation	BCLAF1	IMP		Human	PMID:17938203
Biological Process	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	BCLAF1	IMP		Human	PMID:17938203
Biological Process	GO:0043620	regulation of DNA-templated transcription in response to stress	BCLAF1	IMP		Human	PMID:17938203

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern