Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BCL2L12
  • Mouse genes Bcl2l12
  • Rat genes Bcl2l12
  • Zfish genes bcl2l12
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bcl2l12

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0002039	p53 binding	Bcl2l12	IPI	PR:P02340	Mouse	PMID:20837658
Cellular Component	GO:0016020	membrane	BCL2L12	HDA		Human	PMID:19946888
Cellular Component	GO:0005634	nucleus	BCL2L12	IDA		Human	PMID:20837658
Biological Process	GO:1990001	inhibition of cysteine-type endopeptidase activity involved in apoptotic process	BCL2L12	IDA		Human	PMID:22262180
Biological Process	GO:2000773	negative regulation of cellular senescence	Bcl2l12	IDA		Mouse	PMID:20837658
Biological Process	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	Bcl2l12	IDA		Mouse	PMID:20837658
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	BCL2L12	IDA		Human	PMID:22262180

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern