Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AUTS2
  • Mouse genes Auts2
  • Rat genes
  • Zfish genes auts2a,auts2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Auts2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	AUTS2	IDA		Human	PMID:25519132
Molecular Function	GO:0005515	protein binding	AUTS2	IPI	UniProtKB:Q09472	Human	PMID:25519132
Molecular Function	GO:0005515	protein binding	AUTS2	IPI	UniProtKB:Q86SE9	Human	PMID:25519132
Molecular Function	GO:0005515	protein binding	AUTS2	IPI	UniProtKB:Q86SE9	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	AUTS2	IPI	UniProtKB:Q86SE9	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	Auts2	IPI	UniProtKB:Q99K48	Mouse	MGI:MGI:7260194|PMID:34013328
Molecular Function	GO:0005515	protein binding	Auts2	IPI	PR:Q9CQJ4	Mouse	PMID:25519132
Cellular Component	GO:0015629	actin cytoskeleton	Auts2	IDA		Mouse	MGI:MGI:5908783|PMID:25533347
Cellular Component	GO:0030426	growth cone	Auts2	IDA		Mouse	MGI:MGI:5908783|PMID:25533347
Cellular Component	GO:0005634	nucleus	Auts2	IDA		Mouse	MGI:MGI:4417999|PMID:19948250
Cellular Component	GO:0005634	nucleus	Auts2	IDA		Mouse	MGI:MGI:5908783|PMID:25533347
Cellular Component	GO:0005634	nucleus	Auts2	IDA		Mouse	PMID:25519132
Biological Process	GO:0031532	actin cytoskeleton reorganization	Auts2	IMP		Mouse	MGI:MGI:5908783|PMID:25533347
Biological Process	GO:0048675	axon extension	Auts2	IMP		Mouse	MGI:MGI:5908783|PMID:25533347
Biological Process	GO:0043009	chordate embryonic development	auts2a	IMP	ZFIN:ZDB-MRPHLNO-130212-7	Zfish	PMID:23349641
Biological Process	GO:0043009	chordate embryonic development	auts2a	IMP	ZFIN:ZDB-MRPHLNO-130212-6	Zfish	PMID:23349641
Biological Process	GO:0097484	dendrite extension	Auts2	IMP		Mouse	MGI:MGI:5908783|PMID:25533347
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	auts2a	IMP	ZFIN:ZDB-MRPHLNO-130408-4	Zfish	PMID:23332918
Biological Process	GO:0021884	forebrain neuron development	auts2a	IMP	ZFIN:ZDB-MRPHLNO-130408-4	Zfish	PMID:23332918
Biological Process	GO:0098582	innate vocalization behavior	Auts2	IMP		Mouse	PMID:25519132
Biological Process	GO:0070050	neuron cellular homeostasis	auts2a	IMP	ZFIN:ZDB-MRPHLNO-130212-6	Zfish	PMID:23349641
Biological Process	GO:0001764	neuron migration	Auts2	IMP		Mouse	MGI:MGI:5908783|PMID:25533347
Biological Process	GO:0051571	positive regulation of histone H3-K4 methylation	AUTS2	IDA		Human	PMID:25519132
Biological Process	GO:2000620	positive regulation of histone H4-K16 acetylation	AUTS2	IDA		Human	PMID:25519132
Biological Process	GO:0010592	positive regulation of lamellipodium assembly	Auts2	IMP		Mouse	MGI:MGI:5908783|PMID:25533347
Biological Process	GO:0035022	positive regulation of Rac protein signal transduction	Auts2	IMP		Mouse	MGI:MGI:5908783|PMID:25533347
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	AUTS2	IDA		Human	PMID:25519132
Biological Process	GO:0060013	righting reflex	Auts2	IMP		Mouse	PMID:25519132

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern