Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ATXN2
  • Mouse genes Atxn2
  • Rat genes Atxn2
  • Zfish genes atxn2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Atxn2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005154	epidermal growth factor receptor binding	ATXN2	IPI	UniProtKB:P00533	Human	PMID:18602463
Molecular Function	GO:0005515	protein binding	ATXN2	IPI	UniProtKB:Q9NWB1	Human	PMID:10814712
Molecular Function	GO:0005515	protein binding	ATXN2	IPI	UniProtKB:P11940	Human	PMID:15663938
Molecular Function	GO:0005515	protein binding	ATXN2	IPI	UniProtKB:Q99962	Human	PMID:16115810
Molecular Function	GO:0005515	protein binding	ATXN2	IPI	UniProtKB:Q99963	Human	PMID:16115810
Molecular Function	GO:0005515	protein binding	ATXN2	IPI	UniProtKB:P54253	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	ATXN2	IPI	UniProtKB:Q99962	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	ATXN2	IPI	UniProtKB:Q99963	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	ATXN2	IPI	UniProtKB:O60260	Human	PMID:17097639
Molecular Function	GO:0005515	protein binding	ATXN2	IPI	UniProtKB:P11940	Human	PMID:17392519
Molecular Function	GO:0005515	protein binding	ATXN2	IPI	UniProtKB:P26196	Human	PMID:17392519
Molecular Function	GO:0005515	protein binding	ATXN2	IPI	UniProtKB:Q99962	Human	PMID:18602463
Molecular Function	GO:0005515	protein binding	ATXN2	IPI	UniProtKB:Q99963	Human	PMID:18602463
Molecular Function	GO:0005515	protein binding	ATXN2	IPI	UniProtKB:P11940	Human	PMID:20181956
Molecular Function	GO:0005515	protein binding	ATXN2	IPI	UniProtKB:Q13148	Human	PMID:20740007
Molecular Function	GO:0005515	protein binding	ATXN2	IPI	UniProtKB:Q13283	Human	PMID:23209657
Molecular Function	GO:0005515	protein binding	ATXN2	IPI	UniProtKB:P26196	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	ATXN2	IPI	UniProtKB:P11940	Human	PMID:35044719
Molecular Function	GO:0003723	RNA binding	ATXN2	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	ATXN2	HDA		Human	PMID:22681889
Cellular Component	GO:0005737	cytoplasm	ATXN2	IDA		Human	PMID:10814712
Cellular Component	GO:0005737	cytoplasm	ATXN2	IDA		Human	PMID:10973246
Cellular Component	GO:0005737	cytoplasm	ATXN2	IDA		Human	PMID:17392519
Cellular Component	GO:0005737	cytoplasm	Atxn2	IDA		Mouse	PMID:10973246
Cellular Component	GO:0010494	cytoplasmic stress granule	ATXN2	IDA		Human	PMID:17392519
Cellular Component	GO:0005829	cytosol	ATXN2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	ATXN2	IDA		Human	PMID:12812977
Cellular Component	GO:0005794	Golgi apparatus	ATXN2	IDA		Human	PMID:17097639
Cellular Component	GO:0016020	membrane	ATXN2	HDA		Human	PMID:19946888
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ATXN2	IDA		Human	PMID:17097639
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Atxn2	IDA		Mouse	PMID:11471052
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Atxn2	IDA		Mouse	PMID:9668173
Cellular Component	GO:0005844	polysome	ATXN2	IDA		Human	PMID:16835262
Cellular Component	GO:1990904	ribonucleoprotein complex	ATXN2	IDA		Human	PMID:16835262
Cellular Component	GO:0005802	trans-Golgi network	ATXN2	IDA		Human	PMID:10814712
Biological Process	GO:0021702	cerebellar Purkinje cell differentiation	Atxn2	IMP	MGI:MGI:3505741	Mouse	PMID:10973246
Biological Process	GO:0048872	homeostasis of number of cells	Atxn2	IMP	MGI:MGI:3505741	Mouse	PMID:10973246
Biological Process	GO:0040015	negative regulation of multicellular organism growth	Atxn2	IMP	MGI:MGI:3611805	Mouse	PMID:16293225
Biological Process	GO:0002091	negative regulation of receptor internalization	ATXN2	IMP		Human	PMID:18602463
Biological Process	GO:0050905	neuromuscular process	Atxn2	IMP	MGI:MGI:3505741	Mouse	PMID:10973246
Biological Process	GO:0048812	neuron projection morphogenesis	Atxn2	IMP	MGI:MGI:3505741	Mouse	PMID:10973246
Biological Process	GO:0033962	P-body assembly	ATXN2	IMP		Human	PMID:17392519
Biological Process	GO:0034063	stress granule assembly	ATXN2	IMP		Human	PMID:17392519

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern