Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ATP6V1C1
  • Mouse genes Atp6v1c1
  • Rat genes Atp6v1c1
  • Zfish genes atp6v1c1a,atp6v1c1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Atp6v1c1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	ATP6V1C1	IPI	UniProtKB:P62330	Human	PMID:16415858
Molecular Function	GO:0046961	proton-transporting ATPase activity, rotational mechanism	Atp6v1c1	IDA		Mouse	PMID:12527205
Cellular Component	GO:0045177	apical part of cell	Atp6v1c1	IDA		Rat	PMID:16192400|RGD:1581809
Cellular Component	GO:1904949	ATPase complex	Atp6v1c1	IDA		Mouse	PMID:12527205
Cellular Component	GO:0005737	cytoplasm	Atp6v1c1	IDA		Rat	PMID:16192400|RGD:1581809
Cellular Component	GO:0031410	cytoplasmic vesicle	Atp6v1c1	IDA		Rat	PMID:16192400|RGD:1581809
Cellular Component	GO:0070062	extracellular exosome	ATP6V1C1	HDA		Human	PMID:19056867
Cellular Component	GO:0098850	extrinsic component of synaptic vesicle membrane	Atp6v1c1	EXP		Rat	PMID:32165585|RGD:39458019
Cellular Component	GO:0098850	extrinsic component of synaptic vesicle membrane	Atp6v1c1	IDA		Rat	PMID:32165585|RGD:39458019
Cellular Component	GO:0005765	lysosomal membrane	ATP6V1C1	HDA		Human	PMID:17897319
Cellular Component	GO:0005886	plasma membrane	Atp6v1c1	IDA		Mouse	MGI:MGI:3850618|PMID:16177003
Cellular Component	GO:0005886	plasma membrane	Atp6v1c1	IDA		Rat	PMID:11870875|RGD:14700650
Cellular Component	GO:0033176	proton-transporting V-type ATPase complex	Atp6v1c1	IDA		Mouse	PMID:12527205
Cellular Component	GO:0033180	proton-transporting V-type ATPase, V1 domain	Atp6v1c1	IDA		Mouse	PMID:12527205
Cellular Component	GO:1902495	transmembrane transporter complex	Atp6v1c1	IDA		Mouse	PMID:12527205
Biological Process	GO:0097401	synaptic vesicle lumen acidification	Atp6v1c1	IDA		Mouse	PMID:28793259
Biological Process	GO:0097401	synaptic vesicle lumen acidification	Atp6v1c1	EXP		Mouse	PMID:28793259
Biological Process	GO:0097401	synaptic vesicle lumen acidification	Atp6v1c1	IMP		Mouse	PMID:28793259

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern