Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ASXL2
  • Mouse genes Asxl2
  • Rat genes Asxl2
  • Zfish genes asxl2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Asxl2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Asxl2	IDA		Mouse	PMID:23046516
Molecular Function	GO:0042975	peroxisome proliferator activated receptor binding	ASXL2	IDA		Human	PMID:21047783
Molecular Function	GO:0005515	protein binding	Asxl2	IPI	UniProtKB:Q99PU7	Mouse	PMID:22878500
Cellular Component	GO:0005654	nucleoplasm	ASXL2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Asxl2	IDA		Mouse	PMID:20577743
Biological Process	GO:0007512	adult heart development	Asxl2	IMP	MGI:MGI:3840841	Mouse	PMID:23046516
Biological Process	GO:0035630	bone mineralization involved in bone maturation	Asxl2	IMP	MGI:MGI:3840841	Mouse	PMID:21490954
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Asxl2	IMP	MGI:MGI:3840841	Mouse	PMID:19270745
Biological Process	GO:0007507	heart development	Asxl2	IMP	MGI:MGI:3840841	Mouse	PMID:19270745
Biological Process	GO:0003007	heart morphogenesis	Asxl2	IMP	MGI:MGI:3840841	Mouse	PMID:24860998
Biological Process	GO:0030225	macrophage differentiation	Asxl2	IMP		Mouse	PMID:21490954
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Asxl2	IMP	MGI:MGI:3840841	Mouse	PMID:23046516
Biological Process	GO:0030316	osteoclast differentiation	Asxl2	IMP		Mouse	PMID:21490954
Biological Process	GO:1900159	positive regulation of bone mineralization involved in bone maturation	Asxl2	IMP	MGI:MGI:3840841	Mouse	PMID:21490954
Biological Process	GO:0045600	positive regulation of fat cell differentiation	ASXL2	IDA		Human	PMID:21047783
Biological Process	GO:0010884	positive regulation of lipid storage	Asxl2	IMP		Rat	PMID:24321552|RGD:15023475
Biological Process	GO:0045651	positive regulation of macrophage differentiation	Asxl2	IMP		Mouse	PMID:21490954
Biological Process	GO:0045672	positive regulation of osteoclast differentiation	Asxl2	IMP		Mouse	PMID:21490954
Biological Process	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway	ASXL2	IDA		Human	PMID:21047783
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ASXL2	IDA		Human	PMID:21047783
Biological Process	GO:0051347	positive regulation of transferase activity	Asxl2	IMP	MGI:MGI:3840841	Mouse	PMID:19270745

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern