Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Asic3

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes ASIC3
- Mouse genes Asic3
- Rat genes Asic3
- Zfish genes asic1b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Asic3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042931	enterobactin transmembrane transporter activity	Asic3	IMP	MGI:MGI:2429689	Mouse	PMID:19590043
Molecular Function	GO:0015280	ligand-gated sodium channel activity	Asic3	IDA		Rat	PMID:9261094\|RGD:1299543
Molecular Function	GO:0015280	ligand-gated sodium channel activity	Asic3	IMP		Rat	PMID:9261094\|RGD:1299543
Molecular Function	GO:0015280	ligand-gated sodium channel activity	asic1b	IDA		Zfish	PMID:14970195
Molecular Function	GO:0005261	monoatomic cation channel activity	Asic3	IMP	MGI:MGI:2429689	Mouse	PMID:11854527
Molecular Function	GO:0005261	monoatomic cation channel activity	Asic3	IDA		Mouse	PMID:11854527
Molecular Function	GO:0005515	protein binding	Asic3	IPI	RGD:620380	Rat	PMID:11457882\|RGD:634171
Molecular Function	GO:0005515	protein binding	Asic3	IPI	UniProtKB:Q63ZW7-3	Rat	PMID:11872753\|RGD:8554589
Molecular Function	GO:0005515	protein binding	Asic3	IPI	RGD:708538\|RGD:620380	Rat	PMID:16234233\|RGD:1581392
Molecular Function	GO:0005515	protein binding	Asic3	IPI	UniProtKB:Q920G2	Rat	PMID:16234233\|RGD:1581392
Molecular Function	GO:0005515	protein binding	Asic3	IPI	UniProtKB:Q9JJ19	Rat	PMID:16234233\|RGD:1581392
Molecular Function	GO:0005515	protein binding	Asic3	IPI	UniProtKB:D4A100	Rat	PMID:17167420\|RGD:13432298
Molecular Function	GO:0005515	protein binding	Asic3	IPI	UniProtKB:P54116	Rat	PMID:22850675\|RGD:8553778
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Asic3	IDA		Rat	PMID:16234233\|RGD:1581392
Cellular Component	GO:0005886	plasma membrane	Asic3	IDA		Mouse	PMID:11854527
Cellular Component	GO:0005886	plasma membrane	Asic3	IDA		Rat	PMID:16234233\|RGD:1581392
Cellular Component	GO:0005886	plasma membrane	Asic3	IDA		Rat	PMID:9261094\|RGD:1299543
Cellular Component	GO:0005886	plasma membrane	asic1b	IDA		Zfish	PMID:14970195
Biological Process	GO:0050907	detection of chemical stimulus involved in sensory perception	Asic3	IMP	MGI:MGI:2429689	Mouse	PMID:11754838
Biological Process	GO:0050968	detection of chemical stimulus involved in sensory perception of pain	Asic3	IMP	MGI:MGI:2451051	Mouse	PMID:12060708
Biological Process	GO:0050968	detection of chemical stimulus involved in sensory perception of pain	Asic3	IMP	MGI:MGI:2429689	Mouse	PMID:11754838
Biological Process	GO:0050974	detection of mechanical stimulus involved in sensory perception	Asic3	IMP	MGI:MGI:2429689	Mouse	PMID:11754838
Biological Process	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain	Asic3	IMP	MGI:MGI:2451051	Mouse	PMID:12060708
Biological Process	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain	Asic3	IMP	MGI:MGI:2429689	Mouse	PMID:11754838
Biological Process	GO:0050961	detection of temperature stimulus involved in sensory perception	Asic3	IMP	MGI:MGI:2429689	Mouse	PMID:11754838
Biological Process	GO:0050965	detection of temperature stimulus involved in sensory perception of pain	Asic3	IMP	MGI:MGI:2451051	Mouse	PMID:12060708
Biological Process	GO:0051649	establishment of localization in cell	Asic3	IMP	MGI:MGI:2429689	Mouse	PMID:19590043
Biological Process	GO:0098655	monoatomic cation transmembrane transport	Asic3	IMP	MGI:MGI:2429689	Mouse	MGI:MGI:2158965\|PMID:11854527
Biological Process	GO:0006812	monoatomic cation transport	Asic3	IDA		Mouse	PMID:11854527
Biological Process	GO:0006812	monoatomic cation transport	Asic3	IMP	MGI:MGI:2429689	Mouse	PMID:11854527
Biological Process	GO:0034220	monoatomic ion transmembrane transport	Asic3	IMP	MGI:MGI:2429689	Mouse	PMID:19590043
Biological Process	GO:0034220	monoatomic ion transmembrane transport	Asic3	IDA		Rat	PMID:16234233\|RGD:1581392
Biological Process	GO:0010447	response to acidic pH	Asic3	IMP	MGI:MGI:2451051	Mouse	PMID:12060708
Biological Process	GO:0010447	response to acidic pH	Asic3	IDA		Mouse	PMID:11854527
Biological Process	GO:0010447	response to acidic pH	Asic3	IMP	MGI:MGI:2429689	Mouse	PMID:11754838
Biological Process	GO:0010447	response to acidic pH	Asic3	IMP	MGI:MGI:2429689	Mouse	PMID:11854527
Biological Process	GO:0010447	response to acidic pH	Asic3	IDA		Rat	PMID:9261094\|RGD:1299543
Biological Process	GO:0009408	response to heat	Asic3	IMP	MGI:MGI:2451051	Mouse	PMID:12060708
Biological Process	GO:0009408	response to heat	Asic3	IMP	MGI:MGI:2429689	Mouse	PMID:11754838
Biological Process	GO:0009612	response to mechanical stimulus	Asic3	IMP	MGI:MGI:2429689	Mouse	PMID:11754838
Biological Process	GO:0009612	response to mechanical stimulus	Asic3	IMP	MGI:MGI:2451051	Mouse	PMID:12060708
Biological Process	GO:0050915	sensory perception of sour taste	ASIC3	IMP		Human	PMID:19812697
Biological Process	GO:0006814	sodium ion transport	Asic3	IDA		Rat	PMID:9261094\|RGD:1299543
Biological Process	GO:0006814	sodium ion transport	Asic3	IMP		Rat	PMID:9261094\|RGD:1299543

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/30/2025 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.