Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ARRDC4
  • Mouse genes Arrdc4
  • Rat genes Arrdc4
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arrdc4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	ARRDC4	IPI	UniProtKB:P30518	Human	PMID:23236378
Molecular Function	GO:1990756	ubiquitin ligase-substrate adaptor activity	ARRDC4	IDA		Human	PMID:28594402
Molecular Function	GO:1990756	ubiquitin ligase-substrate adaptor activity	Arrdc4	IMP		Mouse	MGI:MGI:5804712|PMID:27462458
Cellular Component	GO:0005768	endosome	ARRDC4	IDA		Human	PMID:23236378
Cellular Component	GO:1903561	extracellular vesicle	Arrdc4	IDA		Mouse	MGI:MGI:5804712|PMID:27462458
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ARRDC4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	ARRDC4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	ARRDC4	IDA		Human	PMID:23236378
Cellular Component	GO:0005886	plasma membrane	Arrdc4	IDA		Mouse	MGI:MGI:5804712|PMID:27462458
Biological Process	GO:0140112	extracellular vesicle biogenesis	Arrdc4	IMP		Mouse	MGI:MGI:5804712|PMID:27462458
Biological Process	GO:0032728	positive regulation of interferon-beta production	ARRDC4	IDA		Human	PMID:28594402
Biological Process	GO:0051443	positive regulation of ubiquitin-protein transferase activity	ARRDC4	IPI	UniProtKB:Q96PU5	Human	PMID:23236378
Biological Process	GO:0070534	protein K63-linked ubiquitination	ARRDC4	IDA		Human	PMID:28594402
Biological Process	GO:0015031	protein transport	Arrdc4	IMP		Mouse	MGI:MGI:5804712|PMID:27462458
Biological Process	GO:0016567	protein ubiquitination	Arrdc4	IMP		Mouse	MGI:MGI:5804712|PMID:27462458

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern