Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ARPC5
  • Mouse genes Arpc5
  • Rat genes Arpc5
  • Zfish genes arpc5a,arpc5b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arpc5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051015	actin filament binding	ARPC5	IDA		Human	PMID:11741539
Molecular Function	GO:0005515	protein binding	ARPC5	IPI	UniProtKB:P59998	Human	PMID:11162547
Molecular Function	GO:0005200	structural constituent of cytoskeleton	ARPC5	IDA		Human	PMID:11741539
Cellular Component	GO:0005885	Arp2/3 protein complex	ARPC5	IDA		Human	PMID:11741539
Cellular Component	GO:0005768	endosome	Arpc5	IDA		Rat	PMID:17959830|RGD:11567214
Cellular Component	GO:0070062	extracellular exosome	ARPC5	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	ARPC5	HDA		Human	PMID:20458337
Cellular Component	GO:0005925	focal adhesion	ARPC5	HDA		Human	PMID:21423176
Cellular Component	GO:0030426	growth cone	Arpc5	IDA		Rat	PMID:18256280|RGD:2306202
Cellular Component	GO:0030027	lamellipodium	Arpc5	IDA		Mouse	PMID:15294161
Cellular Component	GO:0043005	neuron projection	Arpc5	IDA		Rat	PMID:23459330|RGD:11049475
Biological Process	GO:0051639	actin filament network formation	Arpc5	IMP		Rat	PMID:21281821|RGD:11049483
Biological Process	GO:0034314	Arp2/3 complex-mediated actin nucleation	ARPC5	IDA		Human	PMID:11741539
Biological Process	GO:0016477	cell migration	ARPC5	IMP		Human	PMID:22378351
Biological Process	GO:0097581	lamellipodium organization	Arpc5	IMP		Rat	PMID:21281821|RGD:11049483
Biological Process	GO:0030011	maintenance of cell polarity	Arpc5	IMP		Rat	PMID:21281821|RGD:11049483
Biological Process	GO:0061842	microtubule organizing center localization	Arpc5	IMP		Rat	PMID:21281821|RGD:11049483
Biological Process	GO:0021769	orbitofrontal cortex development	Arpc5	IEP		Rat	PMID:23459330|RGD:11049475
Biological Process	GO:0014909	smooth muscle cell migration	Arpc5	IMP		Rat	PMID:21281821|RGD:11049483

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern