Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ARHGEF28
  • Mouse genes Arhgef28
  • Rat genes Arhgef28
  • Zfish genes arhgef28a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arhgef28

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ARHGEF28	EXP		Human	PMID:11058585
Molecular Function	GO:0005515	protein binding	Arhgef28	IPI	PR:O88522	Mouse	PMID:23892723
Molecular Function	GO:0005515	protein binding	Arhgef28	IPI	PR:P08551	Mouse	PMID:16236762
Molecular Function	GO:0005515	protein binding	Arhgef28	IPI	PR:Q8BXR6	Mouse	PMID:23892723
Molecular Function	GO:0005515	protein binding	Arhgef28	IPI	PR:Q62073	Mouse	PMID:23892723
Biological Process	GO:0007160	cell-matrix adhesion	arhgef28a	IMP	ZFIN:ZDB-MRPHLNO-170817-1	Zfish	PMID:27824130
Biological Process	GO:0021955	central nervous system neuron axonogenesis	Arhgef28	IMP		Mouse	PMID:15378065
Biological Process	GO:0007030	Golgi organization	arhgef28a	IMP	ZFIN:ZDB-MRPHLNO-170817-1	Zfish	PMID:27824130
Biological Process	GO:0060415	muscle tissue morphogenesis	arhgef28a	IGI	ZFIN:ZDB-GENE-080423-1	Zfish	PMID:27824130
Biological Process	GO:0060415	muscle tissue morphogenesis	arhgef28a	IMP	ZFIN:ZDB-MRPHLNO-170817-1	Zfish	PMID:27824130
Biological Process	GO:0060052	neurofilament cytoskeleton organization	Arhgef28	IMP		Mouse	PMID:16236762

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern