Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ARHGEF16
  • Mouse genes Arhgef16
  • Rat genes Arhgef16
  • Zfish genes arhgef16
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arhgef16

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	ARHGEF16	HDA		Human	PMID:25468996
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ARHGEF16	IDA		Human	PMID:20679435
Molecular Function	GO:0030165	PDZ domain binding	ARHGEF16	IPI	UniProtKB:O14907	Human	PMID:21139582
Molecular Function	GO:0005515	protein binding	ARHGEF16	IPI	UniProtKB:P63104	Human	PMID:15161933
Molecular Function	GO:0005515	protein binding	ARHGEF16	IPI	UniProtKB:Q96JJ3	Human	PMID:20679435
Molecular Function	GO:0005515	protein binding	ARHGEF16	IPI	UniProtKB:Q05BK6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ARHGEF16	IPI	UniProtKB:Q8NDC0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ARHGEF16	IPI	UniProtKB:Q92734	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ARHGEF16	IPI	UniProtKB:P63104	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	ARHGEF16	IPI	UniProtKB:Q12959	Human	PMID:30126976
Molecular Function	GO:0005515	protein binding	ARHGEF16	IPI	UniProtKB:Q14160	Human	PMID:30126976
Molecular Function	GO:0005515	protein binding	ARHGEF16	IPI	UniProtKB:Q12959	Human	PMID:32203420
Molecular Function	GO:0005515	protein binding	ARHGEF16	IPI	UniProtKB:Q14160	Human	PMID:32203420
Molecular Function	GO:0005515	protein binding	ARHGEF16	IPI	UniProtKB:P31943	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARHGEF16	IPI	UniProtKB:Q14847-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARHGEF16	IPI	UniProtKB:Q8N9W6-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARHGEF16	IPI	UniProtKB:Q9Y5V3	Human	PMID:32296183
Molecular Function	GO:0030971	receptor tyrosine kinase binding	ARHGEF16	IPI	UniProtKB:P29317	Human	PMID:20679435
Molecular Function	GO:0031267	small GTPase binding	ARHGEF16	IPI	UniProtKB:P63000	Human	PMID:20679435
Molecular Function	GO:0031267	small GTPase binding	ARHGEF16	IPI	UniProtKB:P84095	Human	PMID:20679435
Biological Process	GO:0090630	activation of GTPase activity	ARHGEF16	IMP		Human	PMID:20679435
Biological Process	GO:0090630	activation of GTPase activity	ARHGEF16	IDA		Human	PMID:21139582
Biological Process	GO:0060326	cell chemotaxis	ARHGEF16	IMP		Human	PMID:20679435
Biological Process	GO:1903078	positive regulation of protein localization to plasma membrane	ARHGEF16	IMP		Human	PMID:20679435

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern