Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ARHGEF10
  • Mouse genes Arhgef10
  • Rat genes Arhgef10
  • Zfish genes arhgef10
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arhgef10

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ARHGEF10	IDA		Human	PMID:16896804
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ARHGEF10	IDA		Human	PMID:19635168
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ARHGEF10	IDA		Human	PMID:20042462
Molecular Function	GO:0019894	kinesin binding	ARHGEF10	IPI	UniProtKB:O15066	Human	PMID:19635168
Molecular Function	GO:0005515	protein binding	ARHGEF10	IPI	UniProtKB:O15066	Human	PMID:19635168
Cellular Component	GO:0005813	centrosome	ARHGEF10	IDA		Human	PMID:19635168
Biological Process	GO:0090630	activation of GTPase activity	ARHGEF10	IDA		Human	PMID:16896804
Biological Process	GO:0051298	centrosome duplication	ARHGEF10	IMP		Human	PMID:19635168
Biological Process	GO:0090307	mitotic spindle assembly	ARHGEF10	IMP		Human	PMID:19635168
Biological Process	GO:0022011	myelination in peripheral nervous system	ARHGEF10	IMP		Human	PMID:14508709
Biological Process	GO:0051496	positive regulation of stress fiber assembly	ARHGEF10	IMP		Human	PMID:16896804

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern