Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ARHGEF1
  • Mouse genes Arhgef1
  • Rat genes Arhgef1
  • Zfish genes arhgef1a,arhgef1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arhgef1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	ARHGEF1	IPI	UniProtKB:Q14344	Human	PMID:12681510
Molecular Function	GO:0005515	protein binding	ARHGEF1	IPI	UniProtKB:Q14344	Human	PMID:20300064
Molecular Function	GO:0005515	protein binding	ARHGEF1	IPI	UniProtKB:Q7DB74	Human	PMID:20300064
Molecular Function	GO:0005515	protein binding	ARHGEF1	IPI	UniProtKB:P15884	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Arhgef1	IPI	UniProtKB:Q64727	Mouse	MGI:MGI:3688344|PMID:15102471
Molecular Function	GO:0005515	protein binding	Arhgef1	IPI	PR:Q640L3	Mouse	PMID:17000758
Molecular Function	GO:0003723	RNA binding	ARHGEF1	HDA		Human	PMID:22658674
Cellular Component	GO:0005829	cytosol	ARHGEF1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	ARHGEF1	IDA		Human	GO_REF:0000052
Biological Process	GO:0007019	microtubule depolymerization	Arhgef1	IMP		Rat	PMID:20858895|RGD:7242937

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern