Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ARHGAP5
  • Mouse genes Arhgap5
  • Rat genes Arhgap5
  • Zfish genes arhgap5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arhgap5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	ARHGAP5	IPI	UniProtKB:P61588	Human	PMID:23622247
Molecular Function	GO:0042169	SH2 domain binding	ARHGAP5	IPI	UniProtKB:P20936	Human	PMID:1689011
Cellular Component	GO:0005829	cytosol	ARHGAP5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	ARHGAP5	IDA		Human	GO_REF:0000052
Biological Process	GO:0016477	cell migration	Arhgap5	IMP	MGI:MGI:2179998	Mouse	PMID:17662267
Biological Process	GO:0010631	epithelial cell migration	Arhgap5	IMP	MGI:MGI:2179998	Mouse	PMID:17662267
Biological Process	GO:0030879	mammary gland development	Arhgap5	IMP	MGI:MGI:2179998	Mouse	PMID:17662267
Biological Process	GO:0030879	mammary gland development	Arhgap5	IEP		Rat	PMID:10939588|RGD:2316183
Biological Process	GO:0010634	positive regulation of epithelial cell migration	Arhgap5	IMP	MGI:MGI:2179998	Mouse	PMID:17662267
Biological Process	GO:0002053	positive regulation of mesenchymal cell proliferation	Arhgap5	IMP	MGI:MGI:2179998	Mouse	PMID:17662267
Biological Process	GO:0008361	regulation of cell size	Arhgap5	IMP	MGI:MGI:2179998	Mouse	PMID:12015964

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern