Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AP1B1
  • Mouse genes Ap1b1
  • Rat genes Ap1b1
  • Zfish genes ap1b1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ap1b1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	AP1B1	IPI	UniProtKB:P35585	Human	PMID:23415225
Molecular Function	GO:0005515	protein binding	AP1B1	IPI	UniProtKB:P00533	Human	PMID:24189400
Molecular Function	GO:0005515	protein binding	AP1B1	IPI	UniProtKB:P35585	Human	PMID:24843023
Molecular Function	GO:0005515	protein binding	AP1B1	IPI	UniProtKB:P00533	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	AP1B1	IPI	UniProtKB:O88512	Human	PMID:9733768
Molecular Function	GO:0005515	protein binding	AP1B1	IPI	UniProtKB:P22892	Human	PMID:9733768
Molecular Function	GO:0005515	protein binding	Ap1b1	IPI	UniProtKB:Q9EQW7	Mouse	MGI:MGI:5142383|PMID:11106728
Molecular Function	GO:0005515	protein binding	Ap1b1	IPI	UniProtKB:P22892	Mouse	MGI:MGI:3687727|PMID:9733768
Molecular Function	GO:0019901	protein kinase binding	Ap1b1	IPI	UniProtKB:Q5S007	Mouse	MGI:MGI:4941068|PMID:21307259
Molecular Function	GO:0120283	protein serine/threonine kinase binding	Ap1b1	IPI	RGD:620760	Rat	PMID:20802490|RGD:152995511
Cellular Component	GO:0005829	cytosol	AP1B1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	AP1B1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	AP1B1	IDA		Human	GO_REF:0000052
Biological Process	GO:0048268	clathrin coat assembly	Ap1b1	IDA		Rat	PMID:8262066|RGD:2306271
Biological Process	GO:0050974	detection of mechanical stimulus involved in sensory perception	ap1b1	IMP	ZFIN:ZDB-GENO-980410-242	Zfish	PMID:9491988
Biological Process	GO:0007368	determination of left/right symmetry	Ap1b1	IMP		Mouse	PMID:25807483
Biological Process	GO:0006897	endocytosis	ap1b1	IMP		Zfish	PMID:10526320
Biological Process	GO:0035315	hair cell differentiation	ap1b1	IMP		Zfish	PMID:10526320
Biological Process	GO:0007507	heart development	Ap1b1	IMP		Mouse	PMID:25807483
Biological Process	GO:0048839	inner ear development	ap1b1	IMP	ZFIN:ZDB-GENO-980410-242	Zfish	PMID:9491988
Biological Process	GO:0001822	kidney development	Ap1b1	IMP	MGI:MGI:5433323	Mouse	PMID:27002738
Biological Process	GO:0048884	neuromast development	ap1b1	IMP	ZFIN:ZDB-GENO-980410-242	Zfish	PMID:9491988
Biological Process	GO:1903076	regulation of protein localization to plasma membrane	ap1b1	IMP	ZFIN:ZDB-GENO-130514-2	Zfish	PMID:23593334
Biological Process	GO:2000649	regulation of sodium ion transmembrane transporter activity	ap1b1	IMP	ZFIN:ZDB-GENO-130514-2	Zfish	PMID:23593334

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern