Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AP1AR
  • Mouse genes Ap1ar
  • Rat genes Ap1ar
  • Zfish genes ap1ar
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ap1ar

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035650	AP-1 adaptor complex binding	AP1AR	IDA		Human	PMID:19706427
Molecular Function	GO:0019894	kinesin binding	AP1AR	IDA		Human	PMID:19706427
Cellular Component	GO:0005768	endosome	Ap1ar	IDA		Mouse	PMID:22689987
Cellular Component	GO:0005794	Golgi apparatus	AP1AR	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030133	transport vesicle	AP1AR	IDA		Human	GO_REF:0000054
Biological Process	GO:2000146	negative regulation of cell motility	Ap1ar	IMP		Mouse	PMID:22689987
Biological Process	GO:0001920	negative regulation of receptor recycling	AP1AR	IMP		Human	PMID:19706427
Biological Process	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading	AP1AR	IMP		Human	PMID:22689987
Biological Process	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading	Ap1ar	IMP		Mouse	PMID:22689987
Biological Process	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading	Ap1ar	IMP	MGI:MGI:5439984	Mouse	PMID:22689987
Biological Process	GO:0008104	protein localization	Ap1ar	IMP	MGI:MGI:5439984	Mouse	PMID:22689987
Biological Process	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation	Ap1ar	IMP		Mouse	PMID:22689987
Biological Process	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation	Ap1ar	IGI	MGI:MGI:1923959	Mouse	PMID:22689987
Biological Process	GO:0034446	substrate adhesion-dependent cell spreading	Ap1ar	IMP	MGI:MGI:5439984	Mouse	PMID:22689987
Biological Process	GO:0048203	vesicle targeting, trans-Golgi to endosome	AP1AR	IDA		Human	PMID:19706427

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern