Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ALYREF
  • Mouse genes Alyref2
  • Rat genes Alyref
  • Zfish genes alyref
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Alyref2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0062153	C5-methylcytidine-containing RNA binding	ALYREF	IDA		Human	PMID:28418038
Molecular Function	GO:0005515	protein binding	ALYREF	IPI	UniProtKB:Q9UBU9	Human	PMID:11546874
Molecular Function	GO:0005515	protein binding	ALYREF	IPI	UniProtKB:Q13838	Human	PMID:11979277
Molecular Function	GO:0005515	protein binding	ALYREF	IPI	UniProtKB:Q13838	Human	PMID:14667819
Molecular Function	GO:0005515	protein binding	ALYREF	IPI	UniProtKB:O00148	Human	PMID:15047853
Molecular Function	GO:0005515	protein binding	ALYREF	IPI	UniProtKB:Q13838	Human	PMID:15047853
Molecular Function	GO:0005515	protein binding	ALYREF	IPI	UniProtKB:Q09161	Human	PMID:17190602
Molecular Function	GO:0005515	protein binding	ALYREF	IPI	UniProtKB:Q01780	Human	PMID:17234882
Molecular Function	GO:0005515	protein binding	ALYREF	IPI	UniProtKB:Q96ST2	Human	PMID:17234882
Molecular Function	GO:0005515	protein binding	ALYREF	IPI	UniProtKB:P31749	Human	PMID:18562279
Molecular Function	GO:0005515	protein binding	ALYREF	IPI	UniProtKB:Q13769	Human	PMID:19165146
Molecular Function	GO:0005515	protein binding	ALYREF	IPI	UniProtKB:Q9UBU9	Human	PMID:19165146
Molecular Function	GO:0005515	protein binding	ALYREF	IPI	UniProtKB:Q2HR75	Human	PMID:19850040
Molecular Function	GO:0005515	protein binding	ALYREF	IPI	UniProtKB:Q2HR75	Human	PMID:21814512
Molecular Function	GO:0005515	protein binding	ALYREF	IPI	UniProtKB:Q13838	Human	PMID:23299939
Molecular Function	GO:0005515	protein binding	ALYREF	IPI	UniProtKB:Q9UBU9	Human	PMID:23299939
Molecular Function	GO:0005515	protein binding	ALYREF	IPI	UniProtKB:Q9Y3Y2	Human	PMID:23299939
Molecular Function	GO:0005515	protein binding	ALYREF	IPI	UniProtKB:P06493	Human	PMID:29128334
Molecular Function	GO:0003723	RNA binding	ALYREF	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	ALYREF	HDA		Human	PMID:22681889
Molecular Function	GO:0003723	RNA binding	Alyref2	EXP		Mouse	MGI:MGI:7310202|PMID:24550725
Molecular Function	GO:0003723	RNA binding	Alyref2	EXP		Mouse	MGI:MGI:7310201|PMID:17000901
Molecular Function	GO:0003723	RNA binding	Alyref2	IDA		Mouse	PMID:10786854
Molecular Function	GO:0003697	single-stranded DNA binding	Alyref2	IDA		Mouse	PMID:10786854
Cellular Component	GO:0071013	catalytic step 2 spliceosome	ALYREF	IDA		Human	PMID:11991638
Cellular Component	GO:0000781	chromosome, telomeric region	ALYREF	IDA		Human	PMID:24270157
Cellular Component	GO:0005737	cytoplasm	ALYREF	IDA		Human	PMID:28418038
Cellular Component	GO:0070062	extracellular exosome	ALYREF	HDA		Human	PMID:19056867
Cellular Component	GO:0016020	membrane	ALYREF	HDA		Human	PMID:16210410
Cellular Component	GO:0005634	nucleus	ALYREF	IDA		Human	PMID:28418038
Cellular Component	GO:0000346	transcription export complex	ALYREF	IDA		Human	PMID:15833825
Cellular Component	GO:0000346	transcription export complex	ALYREF	IDA		Human	PMID:15998806
Biological Process	GO:0006406	mRNA export from nucleus	ALYREF	IMP		Human	PMID:17190602
Biological Process	GO:0006406	mRNA export from nucleus	ALYREF	IMP		Human	PMID:25662211
Biological Process	GO:0051028	mRNA transport	Alyref2	IDA		Mouse	MGI:MGI:5520044|PMID:18364396
Biological Process	GO:0001649	osteoblast differentiation	ALYREF	HDA		Human	PMID:16210410
Biological Process	GO:0032786	positive regulation of DNA-templated transcription, elongation	ALYREF	IMP		Human	PMID:22144908
Biological Process	GO:0000018	regulation of DNA recombination	ALYREF	IMP		Human	PMID:22144908
Biological Process	GO:0031297	replication fork processing	ALYREF	IMP		Human	PMID:22144908
Biological Process	GO:0006405	RNA export from nucleus	ALYREF	IDA		Human	PMID:28418038
Biological Process	GO:0046784	viral mRNA export from host cell nucleus	ALYREF	IDA		Human	PMID:18974867

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern