Comparative GO Graph (mouse, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes
  • Mouse genes Alox12e
  • Rat genes Alox12e
  • Zfish genes alox12
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Alox12e

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004052	arachidonate 12(S)-lipoxygenase activity	Alox12e	IMP		Mouse	MGI:MGI:6316908|PMID:11256953
Molecular Function	GO:0004052	arachidonate 12(S)-lipoxygenase activity	alox12	IDA		Zfish	PMID:21880725
Molecular Function	GO:0004052	arachidonate 12(S)-lipoxygenase activity	alox12	IMP	ZFIN:ZDB-MRPHLNO-120130-4	Zfish	PMID:22143766
Molecular Function	GO:0004052	arachidonate 12(S)-lipoxygenase activity	alox12	IMP	ZFIN:ZDB-MRPHLNO-120130-3	Zfish	PMID:22143766
Molecular Function	GO:0004052	arachidonate 12(S)-lipoxygenase activity	alox12	IDA		Zfish	PMID:22143766
Molecular Function	GO:0005509	calcium ion binding	alox12	IDA		Zfish	PMID:28528958
Molecular Function	GO:0016165	linoleate 13S-lipoxygenase activity	Alox12e	IMP		Mouse	MGI:MGI:6316908|PMID:11256953
Molecular Function	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	alox12	IDA		Zfish	PMID:28528958
Cellular Component	GO:0005634	nucleus	alox12	IDA		Zfish	PMID:22143766
Biological Process	GO:0019369	arachidonic acid metabolic process	Alox12e	IMP		Mouse	MGI:MGI:6316908|PMID:11256953
Biological Process	GO:0019369	arachidonic acid metabolic process	Alox12e	IMP		Mouse	MGI:MGI:82948|PMID:8798535
Biological Process	GO:0019369	arachidonic acid metabolic process	Alox12e	IDA		Rat	PMID:23382512|RGD:8554649
Biological Process	GO:0019372	lipoxygenase pathway	Alox12e	IMP		Mouse	MGI:MGI:82948|PMID:8798535
Biological Process	GO:0019372	lipoxygenase pathway	Alox12e	IDA		Rat	PMID:23382512|RGD:8554649

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern