Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ALKBH3
  • Mouse genes Alkbh3
  • Rat genes Alkbh3
  • Zfish genes alkbh3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Alkbh3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016706	2-oxoglutarate-dependent dioxygenase activity	Alkbh3	IDA		Mouse	PMID:16174769
Molecular Function	GO:0051747	cytosine C-5 DNA demethylase activity	Alkbh3	IDA		Mouse	PMID:16174769
Molecular Function	GO:0043734	DNA-N1-methyladenine dioxygenase activity	ALKBH3	IDA		Human	PMID:16858410
Molecular Function	GO:0043734	DNA-N1-methyladenine dioxygenase activity	ALKBH3	IMP		Human	PMID:22055184
Molecular Function	GO:0008198	ferrous iron binding	ALKBH3	IDA		Human	PMID:16858410
Molecular Function	GO:1990930	mRNA N1-methyladenosine dioxygenase activity	ALKBH3	IDA		Human	PMID:26863196
Molecular Function	GO:1990930	mRNA N1-methyladenosine dioxygenase activity	ALKBH3	IDA		Human	PMID:26863410
Molecular Function	GO:0035516	oxidative DNA demethylase activity	ALKBH3	IDA		Human	PMID:12486230
Molecular Function	GO:0035516	oxidative DNA demethylase activity	ALKBH3	IDA		Human	PMID:16174769
Molecular Function	GO:0035516	oxidative DNA demethylase activity	ALKBH3	IDA		Human	PMID:20714506
Molecular Function	GO:0035516	oxidative DNA demethylase activity	Alkbh3	IDA		Mouse	MGI:MGI:3611146|PMID:16174769
Molecular Function	GO:0035515	oxidative RNA demethylase activity	ALKBH3	IDA		Human	PMID:16174769
Molecular Function	GO:0035515	oxidative RNA demethylase activity	Alkbh3	IDA		Mouse	MGI:MGI:3611146|PMID:16174769
Molecular Function	GO:0005515	protein binding	ALKBH3	IPI	UniProtKB:Q8N3C0	Human	PMID:22055184
Molecular Function	GO:0005515	protein binding	ALKBH3	IPI	UniProtKB:O76003	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ALKBH3	IPI	UniProtKB:Q08379	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ALKBH3	IPI	UniProtKB:Q13422	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ALKBH3	IPI	UniProtKB:Q8TBB1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ALKBH3	IPI	UniProtKB:Q96MA6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ALKBH3	IPI	UniProtKB:Q08379	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ALKBH3	IPI	UniProtKB:Q13422	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ALKBH3	IPI	UniProtKB:Q08379	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	ALKBH3	IPI	UniProtKB:Q13422	Human	PMID:31515488
Cellular Component	GO:0005829	cytosol	ALKBH3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	ALKBH3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	ALKBH3	IDA		Human	GO_REF:0000052
Biological Process	GO:0008283	cell population proliferation	ALKBH3	IMP		Human	PMID:22055184
Biological Process	GO:0006307	DNA dealkylation involved in DNA repair	ALKBH3	IDA		Human	PMID:16858410
Biological Process	GO:0006307	DNA dealkylation involved in DNA repair	ALKBH3	IDA		Human	PMID:20714506
Biological Process	GO:0006307	DNA dealkylation involved in DNA repair	ALKBH3	IDA		Human	PMID:22055184
Biological Process	GO:0006281	DNA repair	ALKBH3	IDA		Human	PMID:16858410
Biological Process	GO:0035552	oxidative single-stranded DNA demethylation	ALKBH3	IDA		Human	PMID:16858410
Biological Process	GO:0035552	oxidative single-stranded DNA demethylation	ALKBH3	IMP		Human	PMID:22055184
Biological Process	GO:0035553	oxidative single-stranded RNA demethylation	ALKBH3	IDA		Human	PMID:26863196
Biological Process	GO:0035553	oxidative single-stranded RNA demethylation	ALKBH3	IDA		Human	PMID:26863410

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern