Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ALKBH2
  • Mouse genes Alkbh2
  • Rat genes Alkbh2
  • Zfish genes alkbh2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Alkbh2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016706	2-oxoglutarate-dependent dioxygenase activity	Alkbh2	IDA		Mouse	PMID:16174769
Molecular Function	GO:0051747	cytosine C-5 DNA demethylase activity	ALKBH2	IDA		Human	PMID:18432238
Molecular Function	GO:0051747	cytosine C-5 DNA demethylase activity	Alkbh2	IDA		Mouse	PMID:16174769
Molecular Function	GO:0043734	DNA-N1-methyladenine dioxygenase activity	ALKBH2	IDA		Human	PMID:18432238
Molecular Function	GO:0008198	ferrous iron binding	ALKBH2	IDA		Human	PMID:18432238
Molecular Function	GO:0035516	oxidative DNA demethylase activity	ALKBH2	IDA		Human	PMID:12486230
Molecular Function	GO:0035516	oxidative DNA demethylase activity	ALKBH2	IDA		Human	PMID:16174769
Molecular Function	GO:0035516	oxidative DNA demethylase activity	ALKBH2	IDA		Human	PMID:20714506
Molecular Function	GO:0035516	oxidative DNA demethylase activity	Alkbh2	IDA		Mouse	MGI:MGI:3611146|PMID:16174769
Molecular Function	GO:0035516	oxidative DNA demethylase activity	Alkbh2	IMP		Mouse	MGI:MGI:3796299|PMID:18519673
Molecular Function	GO:0005515	protein binding	ALKBH2	IPI	UniProtKB:P12004	Human	PMID:19736315
Molecular Function	GO:0005515	protein binding	ALKBH2	IPI	UniProtKB:P06748	Human	PMID:23972994
Molecular Function	GO:0005515	protein binding	ALKBH2	IPI	UniProtKB:P12956	Human	PMID:23972994
Molecular Function	GO:0005515	protein binding	ALKBH2	IPI	UniProtKB:P17480	Human	PMID:23972994
Molecular Function	GO:0005515	protein binding	ALKBH2	IPI	UniProtKB:P19338	Human	PMID:23972994
Molecular Function	GO:0005515	protein binding	ALKBH2	IPI	UniProtKB:P12004	Human	PMID:26408825
Molecular Function	GO:0005515	protein binding	ALKBH2	IPI	UniProtKB:Q08379	Human	PMID:32296183
Molecular Function	GO:0000182	rDNA binding	ALKBH2	IDA		Human	PMID:23972994
Cellular Component	GO:0005730	nucleolus	ALKBH2	IDA		Human	PMID:23972994
Cellular Component	GO:0005654	nucleoplasm	ALKBH2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	ALKBH2	IDA		Human	PMID:23972994
Cellular Component	GO:0005634	nucleus	ALKBH2	IDA		Human	PMID:19736315
Biological Process	GO:0006307	DNA dealkylation involved in DNA repair	ALKBH2	IDA		Human	PMID:18432238
Biological Process	GO:0006307	DNA dealkylation involved in DNA repair	ALKBH2	IDA		Human	PMID:20714506
Biological Process	GO:0006307	DNA dealkylation involved in DNA repair	Alkbh2	IMP		Mouse	MGI:MGI:3796299|PMID:18519673

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern