Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ALDH1L2
  • Mouse genes Aldh1l2
  • Rat genes Aldh1l2
  • Zfish genes aldh1l2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Aldh1l2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016155	formyltetrahydrofolate dehydrogenase activity	ALDH1L2	IDA		Human	PMID:21238436
Molecular Function	GO:0016155	formyltetrahydrofolate dehydrogenase activity	Aldh1l2	IMP		Mouse	MGI:MGI:6489626|PMID:33168096
Molecular Function	GO:0005515	protein binding	ALDH1L2	IPI	UniProtKB:P42858	Human	PMID:32814053
Cellular Component	GO:0070062	extracellular exosome	ALDH1L2	HDA		Human	PMID:23533145
Cellular Component	GO:0005739	mitochondrion	ALDH1L2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	ALDH1L2	IDA		Human	PMID:20498374
Cellular Component	GO:0005739	mitochondrion	Aldh1l2	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005654	nucleoplasm	ALDH1L2	IDA		Human	GO_REF:0000052
Biological Process	GO:0009258	10-formyltetrahydrofolate catabolic process	ALDH1L2	IDA		Human	PMID:21238436
Biological Process	GO:0009258	10-formyltetrahydrofolate catabolic process	Aldh1l2	IMP		Mouse	MGI:MGI:6489626|PMID:33168096
Biological Process	GO:0006635	fatty acid beta-oxidation	Aldh1l2	IMP		Mouse	MGI:MGI:6489626|PMID:33168096
Biological Process	GO:0046655	folic acid metabolic process	Aldh1l2	IMP		Mouse	MGI:MGI:6489626|PMID:33168096
Biological Process	GO:0006740	NADPH regeneration	ALDH1L2	IDA		Human	PMID:21238436
Biological Process	GO:0006740	NADPH regeneration	Aldh1l2	IMP		Mouse	MGI:MGI:6489626|PMID:33168096

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern