Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AK1
  • Mouse genes Ak1
  • Rat genes Ak1
  • Zfish genes ak1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ak1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004017	adenylate kinase activity	AK1	EXP		Human	PMID:211388
Molecular Function	GO:0004017	adenylate kinase activity	AK1	EXP		Human	PMID:2542324
Molecular Function	GO:0004017	adenylate kinase activity	Ak1	IDA		Mouse	PMID:198184
Molecular Function	GO:0004017	adenylate kinase activity	Ak1	IDA		Mouse	PMID:7323947
Molecular Function	GO:0004017	adenylate kinase activity	Ak1	IDA		Mouse	PMID:7444718
Molecular Function	GO:0004017	adenylate kinase activity	Ak1	IDA		Rat	PMID:8468325|RGD:5490217
Molecular Function	GO:0004550	nucleoside diphosphate kinase activity	AK1	IDA		Human	PMID:23416111
Molecular Function	GO:0016776	phosphotransferase activity, phosphate group as acceptor	Ak1	IDA		Rat	PMID:19049516|RGD:5134369
Cellular Component	GO:0005829	cytosol	AK1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	AK1	HDA		Human	PMID:19056867
Cellular Component	GO:0043005	neuron projection	Ak1	IDA		Rat	PMID:9648858|RGD:1599010
Cellular Component	GO:0001520	outer dense fiber	Ak1	IDA		Mouse	PMID:16790685
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Ak1	IDA		Rat	PMID:9648858|RGD:1599010
Cellular Component	GO:0030017	sarcomere	Ak1	IDA		Rat	PMID:12432079|RGD:5490518
Cellular Component	GO:0036126	sperm flagellum	Ak1	IDA		Mouse	PMID:16790685
Biological Process	GO:0006172	ADP biosynthetic process	Ak1	IDA		Rat	PMID:19049516|RGD:5134369
Biological Process	GO:0046033	AMP metabolic process	Ak1	IDA		Rat	PMID:19049516|RGD:5134369
Biological Process	GO:0021549	cerebellum development	Ak1	IEP		Rat	PMID:9920788|RGD:632499
Biological Process	GO:0046103	inosine biosynthetic process	Ak1	IDA		Rat	PMID:19049516|RGD:5134369
Biological Process	GO:0007517	muscle organ development	Ak1	IEP		Rat	PMID:8468325|RGD:5490217
Biological Process	GO:0030182	neuron differentiation	Ak1	IEP		Rat	PMID:10101232|RGD:727267
Biological Process	GO:0046940	nucleoside monophosphate phosphorylation	Ak1	IDA		Mouse	MGI:MGI:55148|PMID:7323947
Biological Process	GO:0009142	nucleoside triphosphate biosynthetic process	AK1	IDA		Human	PMID:23416111
Biological Process	GO:0021772	olfactory bulb development	Ak1	IEP		Rat	PMID:9920788|RGD:632499
Biological Process	GO:0010828	positive regulation of glucose transmembrane transport	Ak1	IMP		Rat	PMID:21059655|RGD:5134355
Biological Process	GO:0014042	positive regulation of neuron maturation	Ak1	IEP		Rat	PMID:9920788|RGD:632499
Biological Process	GO:0014823	response to activity	Ak1	IEP		Rat	PMID:17002673|RGD:5490161
Biological Process	GO:0032355	response to estradiol	Ak1	IEP		Rat	PMID:10383487|RGD:5490212
Biological Process	GO:0033574	response to testosterone	Ak1	IEP		Rat	PMID:10383487|RGD:5490212
Biological Process	GO:0009410	response to xenobiotic stimulus	Ak1	IEP		Rat	PMID:17058275|RGD:2301763

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern