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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Ago4

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ago4
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0003725double-stranded RNA bindingAGO4IDAHumanPMID:19966796
Molecular FunctionGO:0035198miRNA bindingAGO4IDAHumanPMID:15260970
Molecular FunctionGO:0005515protein bindingAGO4IPIUniProtKB:P26651HumanPMID:15766526
Molecular FunctionGO:0005515protein bindingAGO4IPIUniProtKB:O15397HumanPMID:19167051
Molecular FunctionGO:0005515protein bindingAGO4IPIUniProtKB:Q8NDV7HumanPMID:19167051
Molecular FunctionGO:0005515protein bindingAGO4IPIUniProtKB:Q8NDV7HumanPMID:19324964
Molecular FunctionGO:0005515protein bindingAGO4IPIUniProtKB:Q8NDV7HumanPMID:19383768
Molecular FunctionGO:0003723RNA bindingAgo4IDAMousePMID:19536157
Molecular FunctionGO:0003727single-stranded RNA bindingAGO4IDAHumanPMID:19966796
Cellular ComponentGO:0005737cytoplasmAGO4IDAHumanPMID:15260970
Cellular ComponentGO:0036464cytoplasmic ribonucleoprotein granuleAGO4IDAHumanGO_REF:0000052
Cellular ComponentGO:0005829cytosolAGO4IDAHumanGO_REF:0000052
Cellular ComponentGO:0016020membraneAGO4HDAHumanPMID:19946888
Cellular ComponentGO:0005634nucleusAgo4IDAMousePMID:22863743
Cellular ComponentGO:0000932P-bodyAgo4IDAMousePMID:19898466
Cellular ComponentGO:0016442RISC complexAGO4IDAHumanPMID:15260970
Cellular ComponentGO:0016442RISC complexAGO4IDAHumanPMID:19966796
Cellular ComponentGO:0016442RISC complexAgo4IDAMousePMID:19536157
Cellular ComponentGO:0070578RISC-loading complexAGO4IDAHumanPMID:19966796
Biological ProcessGO:0008584male gonad developmentAgo4IMPMGI:MGI:5438526MousePMID:22863743
Biological ProcessGO:0007140male meiotic nuclear divisionAgo4IMPMGI:MGI:5438526MousePMID:22863743
Biological ProcessGO:0010586miRNA metabolic processAgo4IMPMGI:MGI:5438526MousePMID:22863743
Biological ProcessGO:0035196miRNA processingAGO4IMPHumanPMID:22795694
Biological ProcessGO:0035278miRNA-mediated gene silencing by inhibition of translationAGO4IDAHumanPMID:18771919
Biological ProcessGO:0006402mRNA catabolic processAGO4IDAHumanPMID:18771919
Biological ProcessGO:0043066negative regulation of apoptotic processAgo4IMPMGI:MGI:5438526MousePMID:22863743
Biological ProcessGO:0031054pre-miRNA processingAGO4IDAHumanPMID:19966796
Biological ProcessGO:0022604regulation of cell morphogenesisAgo4IMPMGI:MGI:5438526MousePMID:22863743
Biological ProcessGO:0070922RISC complex assemblyAGO4IDAHumanPMID:19966796
Biological ProcessGO:0010501RNA secondary structure unwindingAGO4IDAHumanPMID:19966796
Biological ProcessGO:0010501RNA secondary structure unwindingAGO4IMPHumanPMID:22795694
Biological ProcessGO:0007130synaptonemal complex assemblyAgo4IMPMGI:MGI:5438526MousePMID:22863743

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory