Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AFG1L
  • Mouse genes Afg1l
  • Rat genes Afg1l
  • Zfish genes afg1la,afg1lb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Afg1l

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	AFG1L	IPI	UniProtKB:Q8N9N5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	AFG1L	IPI	UniProtKB:P13073	Human	PMID:26759378
Molecular Function	GO:0005515	protein binding	AFG1L	IPI	UniProtKB:P20674	Human	PMID:26759378
Molecular Function	GO:0005515	protein binding	AFG1L	IPI	UniProtKB:Q96TA2	Human	PMID:26759378
Molecular Function	GO:0005515	protein binding	AFG1L	IPI	UniProtKB:P04637	Human	PMID:27323408
Molecular Function	GO:0005515	protein binding	AFG1L	IPI	UniProtKB:Q9UHD4	Human	PMID:32296183
Cellular Component	GO:0005737	cytoplasm	afg1lb	IDA		Zfish	PMID:25139857
Cellular Component	GO:0031966	mitochondrial membrane	AFG1L	IDA		Human	PMID:26759378
Cellular Component	GO:0005739	mitochondrion	AFG1L	IDA		Human	PMID:27323408
Cellular Component	GO:0005739	mitochondrion	Afg1l	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005634	nucleus	afg1lb	IDA		Zfish	PMID:25139857
Biological Process	GO:0003341	cilium movement	afg1lb	IMP	ZFIN:ZDB-MRPHLNO-141110-16	Zfish	PMID:25139857
Biological Process	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen	AFG1L	IMP		Human	PMID:27323408
Biological Process	GO:0035694	mitochondrial protein catabolic process	AFG1L	IMP		Human	PMID:26759378
Biological Process	GO:0007005	mitochondrion organization	AFG1L	IMP		Human	PMID:26759378

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern