Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ADH5
  • Mouse genes Adh5
  • Rat genes Adh5
  • Zfish genes adh5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Adh5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004022	alcohol dehydrogenase (NAD+) activity	Adh5	IDA		Mouse	PMID:3996732
Molecular Function	GO:0004022	alcohol dehydrogenase (NAD+) activity	Adh5	IDA		Rat	PMID:18207224|RGD:5129089
Molecular Function	GO:0005504	fatty acid binding	ADH5	IDA		Human	PMID:8460164
Molecular Function	GO:0018467	formaldehyde dehydrogenase activity	ADH5	IDA		Human	PMID:8460164
Molecular Function	GO:0042802	identical protein binding	Adh5	IPI	PR:P28474	Mouse	PMID:3996732
Molecular Function	GO:0051903	S-(hydroxymethyl)glutathione dehydrogenase activity	Adh5	IMP	MGI:MGI:3033711	Mouse	PMID:15919956
Molecular Function	GO:0008270	zinc ion binding	ADH5	IDA		Human	PMID:6375718
Cellular Component	GO:0005737	cytoplasm	Adh5	IDA		Rat	PMID:1453005|RGD:1357171
Cellular Component	GO:0070062	extracellular exosome	ADH5	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	ADH5	HDA		Human	PMID:23533145
Cellular Component	GO:0005739	mitochondrion	Adh5	IDA		Mouse	PMID:3996732
Cellular Component	GO:0005634	nucleus	Adh5	IDA		Rat	PMID:1453005|RGD:1357171
Biological Process	GO:0007568	aging	Adh5	IEP		Rat	PMID:18207224|RGD:5129089
Biological Process	GO:0006068	ethanol catabolic process	Adh5	IDA		Rat	PMID:18207224|RGD:5129089
Biological Process	GO:0010430	fatty acid omega-oxidation	ADH5	IDA		Human	PMID:16081420
Biological Process	GO:0046294	formaldehyde catabolic process	Adh5	IMP	MGI:MGI:2180100	Mouse	PMID:10358022
Biological Process	GO:0018119	peptidyl-cysteine S-nitrosylation	Adh5	IMP	MGI:MGI:3033711	Mouse	PMID:14980227
Biological Process	GO:0045777	positive regulation of blood pressure	Adh5	IMP	MGI:MGI:3033711	Mouse	PMID:14980227
Biological Process	GO:0003016	respiratory system process	Adh5	IMP	MGI:MGI:3033711	Mouse	PMID:15919956
Biological Process	GO:0032496	response to lipopolysaccharide	Adh5	IMP	MGI:MGI:3033711	Mouse	PMID:14980227
Biological Process	GO:0051409	response to nitrosative stress	Adh5	IMP	MGI:MGI:3033711	Mouse	PMID:14980227
Biological Process	GO:0051775	response to redox state	ADH5	IDA		Human	PMID:8460164
Biological Process	GO:0001523	retinoid metabolic process	Adh5	IMP	MGI:MGI:2180101	Mouse	PMID:12027900

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern