Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ADCY10
  • Mouse genes Adcy10
  • Rat genes Adcy10
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Adcy10

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004016	adenylate cyclase activity	ADCY10	IDA		Human	PMID:12609998
Molecular Function	GO:0004016	adenylate cyclase activity	ADCY10	IDA		Human	PMID:15659711
Molecular Function	GO:0004016	adenylate cyclase activity	Adcy10	IDA		Rat	PMID:7225326|RGD:2313177
Molecular Function	GO:0004016	adenylate cyclase activity	Adcy10	IDA		Rat	PMID:9874775|RGD:1299450
Molecular Function	GO:0051117	ATPase binding	Adcy10	IPI	RGD:1310619	Rat	PMID:17959750|RGD:2313310
Molecular Function	GO:0071890	bicarbonate binding	ADCY10	IDA		Human	PMID:24567411
Molecular Function	GO:0030145	manganese ion binding	Adcy10	IDA		Rat	PMID:7225326|RGD:2313177
Molecular Function	GO:0005515	protein binding	Adcy10	IPI	UniProtKB:Q6UJY2	Mouse	MGI:MGI:3713971|PMID:17517652
Cellular Component	GO:0045177	apical part of cell	Adcy10	IDA		Rat	PMID:17959750|RGD:2313310
Cellular Component	GO:0016324	apical plasma membrane	Adcy10	IDA		Mouse	PMID:17959750
Cellular Component	GO:0030424	axon	Adcy10	IDA		Rat	PMID:16964251|RGD:2313171
Cellular Component	GO:0045178	basal part of cell	Adcy10	IDA		Rat	PMID:17959750|RGD:2313310
Cellular Component	GO:0005737	cytoplasm	Adcy10	IDA		Rat	PMID:16627466|RGD:2313173
Cellular Component	GO:0005829	cytosol	Adcy10	IDA		Rat	PMID:9874775|RGD:1299450
Cellular Component	GO:0030425	dendrite	Adcy10	IDA		Rat	PMID:16964251|RGD:2313171
Cellular Component	GO:0030426	growth cone	Adcy10	IDA		Rat	PMID:16964251|RGD:2313171
Cellular Component	GO:0016020	membrane	Adcy10	IDA		Mouse	PMID:19144954
Cellular Component	GO:0015630	microtubule cytoskeleton	ADCY10	IDA		Human	PMID:15659711
Cellular Component	GO:0031514	motile cilium	ADCY10	IDA		Human	PMID:17591988
Cellular Component	GO:0043025	neuronal cell body	Adcy10	IDA		Rat	PMID:16964251|RGD:2313171
Cellular Component	GO:0005634	nucleus	ADCY10	IDA		Human	PMID:15659711
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ADCY10	IDA		Human	PMID:15659711
Biological Process	GO:0006171	cAMP biosynthetic process	ADCY10	IDA		Human	PMID:12609998
Biological Process	GO:0006171	cAMP biosynthetic process	ADCY10	IDA		Human	PMID:15659711
Biological Process	GO:0006171	cAMP biosynthetic process	Adcy10	IMP		Rat	PMID:16627466|RGD:2313173
Biological Process	GO:0006171	cAMP biosynthetic process	Adcy10	IMP		Rat	PMID:16964251|RGD:2313171
Biological Process	GO:0006171	cAMP biosynthetic process	Adcy10	IDA		Rat	PMID:7225326|RGD:2313177
Biological Process	GO:0006171	cAMP biosynthetic process	Adcy10	IDA		Rat	PMID:9874775|RGD:1299450
Biological Process	GO:0071241	cellular response to inorganic substance	ADCY10	IDA		Human	PMID:12609998
Biological Process	GO:0003351	epithelial cilium movement involved in extracellular fluid movement	ADCY10	IMP		Human	PMID:17591988
Biological Process	GO:0043065	positive regulation of apoptotic process	Adcy10	IMP		Rat	PMID:19336406|RGD:2313274

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern