Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Acsl5

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes ACSL5
- Mouse genes Acsl5
- Rat genes Acsl5
- Zfish genes acsl5
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Acsl5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0047676	arachidonate-CoA ligase activity	Acsl5	IDA		Rat	PMID:28209804\|RGD:14697717
Molecular Function	GO:0004467	long-chain fatty acid-CoA ligase activity	ACSL5	IMP		Human	PMID:22633490
Molecular Function	GO:0004467	long-chain fatty acid-CoA ligase activity	ACSL5	IDA		Human	PMID:24269233
Molecular Function	GO:0004467	long-chain fatty acid-CoA ligase activity	Acsl5	IMP		Mouse	MGI:MGI:6355833\|PMID:22633490
Molecular Function	GO:0004467	long-chain fatty acid-CoA ligase activity	Acsl5	IMP		Rat	PMID:22633490\|RGD:14697723
Molecular Function	GO:0004467	long-chain fatty acid-CoA ligase activity	Acsl5	IDA		Rat	PMID:28209804\|RGD:14697717
Molecular Function	GO:0004467	long-chain fatty acid-CoA ligase activity	Acsl5	IDA		Rat	PMID:9722683\|RGD:69375
Molecular Function	GO:0005515	protein binding	ACSL5	IPI	UniProtKB:O00559	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ACSL5	IPI	UniProtKB:O00623	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ACSL5	IPI	UniProtKB:O60669	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ACSL5	IPI	UniProtKB:Q13520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ACSL5	IPI	UniProtKB:Q14973	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ACSL5	IPI	UniProtKB:Q3KNW5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ACSL5	IPI	UniProtKB:Q86VR2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ACSL5	IPI	UniProtKB:Q8TBB6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ACSL5	IPI	UniProtKB:Q8WU57	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ACSL5	IPI	UniProtKB:Q9NQQ7-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ACSL5	IPI	UniProtKB:Q9NUH8	Human	PMID:32296183
Cellular Component	GO:0005783	endoplasmic reticulum	ACSL5	IDA		Human	PMID:24269233
Cellular Component	GO:0005783	endoplasmic reticulum	Acsl5	IDA		Rat	PMID:16263710\|RGD:2312807
Cellular Component	GO:0016020	membrane	ACSL5	HDA		Human	PMID:19946888
Cellular Component	GO:0005743	mitochondrial inner membrane	Acsl5	HDA		Mouse	PMID:12865426
Cellular Component	GO:0005739	mitochondrion	ACSL5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	Acsl5	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Acsl5	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Acsl5	IDA		Rat	PMID:12147264\|RGD:2312803
Cellular Component	GO:0005730	nucleolus	ACSL5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	ACSL5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	ACSL5	IDA		Human	PMID:24269233
Biological Process	GO:0032869	cellular response to insulin stimulus	Acsl5	IEP		Rat	PMID:16198472\|RGD:2312808
Biological Process	GO:0015908	fatty acid transport	Acsl5	IGI	ECOGENE:EG11530	Rat	PMID:14711823\|RGD:2312802
Biological Process	GO:0001676	long-chain fatty acid metabolic process	ACSL5	IMP		Human	PMID:22633490
Biological Process	GO:0001676	long-chain fatty acid metabolic process	ACSL5	IDA		Human	PMID:24269233
Biological Process	GO:0001676	long-chain fatty acid metabolic process	Acsl5	IMP		Mouse	MGI:MGI:6355833\|PMID:22633490
Biological Process	GO:0001676	long-chain fatty acid metabolic process	Acsl5	IMP		Rat	PMID:22633490\|RGD:14697723
Biological Process	GO:0001676	long-chain fatty acid metabolic process	Acsl5	IDA		Rat	PMID:28209804\|RGD:14697717
Biological Process	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process	Acsl5	IGI	SGD:S000005844\|SGD:S000004860	Rat	PMID:16466685\|RGD:2312800
Biological Process	GO:0008654	phospholipid biosynthetic process	Acsl5	IGI	ECOGENE:EG11530\|ECOGENE:EG10281	Rat	PMID:14711823\|RGD:2312802
Biological Process	GO:0032000	positive regulation of fatty acid beta-oxidation	Acsl5	IGI	ECOGENE:EG11530\|ECOGENE:EG10281	Rat	PMID:14711823\|RGD:2312802
Biological Process	GO:0010747	positive regulation of long-chain fatty acid import across plasma membrane	Acsl5	IDA		Rat	PMID:16263710\|RGD:2312807
Biological Process	GO:0010867	positive regulation of triglyceride biosynthetic process	Acsl5	IDA		Rat	PMID:16263710\|RGD:2312807
Biological Process	GO:0070723	response to cholesterol	Acsl5	IEP		Rat	PMID:9722683\|RGD:69375
Biological Process	GO:0009749	response to glucose	Acsl5	IEP		Rat	PMID:16198472\|RGD:2312808
Biological Process	GO:0007584	response to nutrient	Acsl5	IEP		Rat	PMID:16772660\|RGD:1599807
Biological Process	GO:0009744	response to sucrose	Acsl5	IEP		Rat	PMID:9722683\|RGD:69375

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.