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Gene Ontology Browser
Term Detail
GO term:long-chain fatty acid-CoA ligase activity
Synonym: ACS3
Synonym: acyl-activating enzyme activity
Synonym: acyl-CoA synthetase activity
Synonym: arachidonyl-CoA synthetase
Synonym: FAA1
Synonym: fatty acid thiokinase (long chain) activity
Synonym: fatty acid thiokinase (long-chain) activity
Synonym: LCFA synthetase activity
Synonym: lignoceroyl-CoA synthase activity
Synonym: long-chain acyl CoA synthetase activity
Synonym: long-chain acyl-CoA synthetase activity
Synonym: long-chain acyl-CoA synthetase I
Synonym: long-chain acyl-CoA synthetase II
Synonym: long-chain acyl-coenzyme A synthetase activity
Synonym: long-chain fatty acid activation
Synonym: long-chain-fatty-acid-CoA ligase activity
Synonym: long chain fatty acyl-CoA synthetase activity
Synonym: long-chain-fatty-acyl-CoA synthetase activity
Synonym: long-chain fatty acyl coenzyme A synthetase activity
Synonym: oleoyl-CoA synthetase
Synonym: palmitoyl-CoA ligase
Synonym: palmitoyl-CoA synthase
Synonym: palmitoyl coenzyme A synthetase
Synonym: pristanoyl-CoA synthetase
Synonym: stearoyl-CoA synthetase
Synonym: thiokinase
GO id:GO:0004467
Definition:Catalysis of the reaction: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA; a long-chain fatty acid is a fatty acid with a chain length between C13 and C22.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-aligase activity
                                is-aligase activity, forming carbon-sulfur bonds
                                        is-afatty acid ligase activity
                                                is-along-chain fatty acid [acyl-carrier-protein] ligase activity
                                                is-along-chain fatty acid-CoA ligase activity [GO:0004467] (13 genes, 22 annotations)
                                                        is-amyristoyl-CoA ligase activity
                                                        is-aoleoyl-CoA ligase activity
                                                        is-apalmitoyl-CoA ligase activity
                                                is-amedium-chain fatty acid-CoA ligase activity
                                                is-ashort-chain fatty acid-CoA ligase activity
                                                is-avery long-chain fatty acid-CoA ligase activity


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory