Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ACLY
  • Mouse genes Acly
  • Rat genes Acly
  • Zfish genes aclya,aclyb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Acly

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003878	ATP citrate synthase activity	ACLY	IDA		Human	PMID:10653665
Molecular Function	GO:0003878	ATP citrate synthase activity	ACLY	IDA		Human	PMID:1371749
Molecular Function	GO:0003878	ATP citrate synthase activity	ACLY	IDA		Human	PMID:19286649
Molecular Function	GO:0003878	ATP citrate synthase activity	ACLY	IDA		Human	PMID:9116495
Molecular Function	GO:0003878	ATP citrate synthase activity	Acly	IDA		Mouse	MGI:MGI:6316408|PMID:25450640
Molecular Function	GO:0003878	ATP citrate synthase activity	Acly	IDA		Rat	PMID:11735100|RGD:2317316
Molecular Function	GO:0003878	ATP citrate synthase activity	Acly	IDA		Rat	PMID:18062843|RGD:2317315
Molecular Function	GO:0003878	ATP citrate synthase activity	Acly	IDA		Rat	PMID:2295639|RGD:631761
Molecular Function	GO:0003878	ATP citrate synthase activity	Acly	IDA		Rat	PMID:9116495|RGD:14402438
Molecular Function	GO:0005515	protein binding	ACLY	IPI	UniProtKB:Q5T4S7	Human	PMID:23932781
Molecular Function	GO:0005515	protein binding	ACLY	IPI	UniProtKB:Q8IXJ6	Human	PMID:23932781
Molecular Function	GO:0005515	protein binding	ACLY	IPI	UniProtKB:Q92831	Human	PMID:23932781
Molecular Function	GO:0005515	protein binding	Acly	IPI	UniProtKB:Q8CFN5-4	Mouse	MGI:MGI:3688344|PMID:15102471
Cellular Component	GO:0005829	cytosol	ACLY	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	ACLY	IDA		Human	PMID:9116495
Cellular Component	GO:0070062	extracellular exosome	ACLY	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	ACLY	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	ACLY	HDA		Human	PMID:23533145
Cellular Component	GO:0016020	membrane	ACLY	HDA		Human	PMID:19946888
Cellular Component	GO:0005739	mitochondrion	Acly	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005654	nucleoplasm	ACLY	IDA		Human	GO_REF:0000052
Biological Process	GO:0006085	acetyl-CoA biosynthetic process	ACLY	IDA		Human	PMID:1371749
Biological Process	GO:0006084	acetyl-CoA metabolic process	Acly	IDA		Rat	PMID:18062843|RGD:2317315
Biological Process	GO:0006101	citrate metabolic process	ACLY	IDA		Human	PMID:1371749
Biological Process	GO:0006101	citrate metabolic process	Acly	IDA		Rat	PMID:18062843|RGD:2317315
Biological Process	GO:0006633	fatty acid biosynthetic process	ACLY	IDA		Human	PMID:10653665
Biological Process	GO:0006633	fatty acid biosynthetic process	ACLY	IDA		Human	PMID:19286649
Biological Process	GO:0006633	fatty acid biosynthetic process	Acly	IDA		Rat	PMID:11735100|RGD:2317316
Biological Process	GO:0008610	lipid biosynthetic process	ACLY	IDA		Human	PMID:23932781
Biological Process	GO:0006629	lipid metabolic process	Acly	IEP		Rat	PMID:2295639|RGD:631761
Biological Process	GO:0006107	oxaloacetate metabolic process	ACLY	IDA		Human	PMID:1371749

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern