Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ABRA
  • Mouse genes Abra
  • Rat genes Abra
  • Zfish genes abraa,abrab
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Abra

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Abra	IDA		Mouse	MGI:MGI:3694148|PMID:11983702
Molecular Function	GO:0005515	protein binding	ABRA	IPI	UniProtKB:Q6NYC8	Human	PMID:32296183
Cellular Component	GO:0015629	actin cytoskeleton	Abra	IDA		Mouse	MGI:MGI:3694148|PMID:11983702
Cellular Component	GO:0030016	myofibril	Abra	IDA		Mouse	PMID:17194709
Cellular Component	GO:0005886	plasma membrane	ABRA	IDA		Human	GO_REF:0000054
Cellular Component	GO:0030017	sarcomere	Abra	IDA		Rat	PMID:11983702|RGD:8554061
Biological Process	GO:0008015	blood circulation	abraa	IMP	ZFIN:ZDB-MRPHLNO-120730-4	Zfish	PMID:22815879
Biological Process	GO:0007507	heart development	abraa	IMP	ZFIN:ZDB-MRPHLNO-120730-4	Zfish	PMID:22815879
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	Abra	IDA		Mouse	MGI:MGI:3694148|PMID:11983702
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Abra	IDA		Mouse	PMID:15798203
Biological Process	GO:0035025	positive regulation of Rho protein signal transduction	Abra	IDA		Mouse	MGI:MGI:3694148|PMID:11983702
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Abra	IGI	MGI:MGI:2442582	Mouse	PMID:17194709
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Abra	IGI	MGI:MGI:1194500	Mouse	PMID:17194709
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Abra	IDA		Mouse	PMID:17194709
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Abra	IGI	MGI:MGI:2385758	Mouse	PMID:17194709
Biological Process	GO:0035775	pronephric glomerulus morphogenesis	abrab	IGI	ZFIN:ZDB-MRPHLNO-050824-3,ZFIN:ZDB-MRPHLNO-050824-4,ZFIN:ZDB-MRPHLNO-140317-1	Zfish	PMID:23990680
Biological Process	GO:0035775	pronephric glomerulus morphogenesis	abrab	IMP	ZFIN:ZDB-MRPHLNO-140317-1	Zfish	PMID:23990680
Biological Process	GO:0006606	protein import into nucleus	Abra	IDA		Mouse	PMID:15798203
Biological Process	GO:0006366	transcription by RNA polymerase II	Abra	IGI	MGI:MGI:1194500	Mouse	PMID:17194709
Biological Process	GO:0006366	transcription by RNA polymerase II	Abra	IDA		Mouse	PMID:17194709
Biological Process	GO:0006366	transcription by RNA polymerase II	Abra	IGI	MGI:MGI:2442582	Mouse	PMID:17194709
Biological Process	GO:0006366	transcription by RNA polymerase II	Abra	IGI	MGI:MGI:2385758	Mouse	PMID:17194709

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern