Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ABCB8
  • Mouse genes Abcb8
  • Rat genes Abcb8
  • Zfish genes abcb8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Abcb8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	ABCB8	IDA		Human	PMID:31435016
Molecular Function	GO:0005515	protein binding	ABCB8	IPI	UniProtKB:Q9H8K7	Human	PMID:25063848
Molecular Function	GO:0005515	protein binding	ABCB8	IPI	UniProtKB:Q96ER9	Human	PMID:31435016
Cellular Component	GO:0062157	mitochondrial ATP-gated potassium channel complex	ABCB8	IPI		Human	PMID:31435016
Cellular Component	GO:0062157	mitochondrial ATP-gated potassium channel complex	ABCB8	IDA		Human	PMID:31435016
Cellular Component	GO:0062157	mitochondrial ATP-gated potassium channel complex	Abcb8	IPI		Mouse	MGI:MGI:6368416|PMID:31435016
Cellular Component	GO:0031966	mitochondrial membrane	ABCB8	IDA		Human	PMID:9878413
Cellular Component	GO:0005739	mitochondrion	ABCB8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	ABCB8	IDA		Human	PMID:22655043
Cellular Component	GO:0005739	mitochondrion	Abcb8	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005730	nucleolus	ABCB8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	ABCB8	IDA		Human	GO_REF:0000052
Biological Process	GO:0006884	cell volume homeostasis	ABCB8	IDA		Human	PMID:31435016
Biological Process	GO:0140141	mitochondrial potassium ion transmembrane transport	ABCB8	IDA		Human	PMID:31435016
Biological Process	GO:0071805	potassium ion transmembrane transport	ABCB8	IDA		Human	PMID:31435016

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern