Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KIAA0586
  • Mouse genes 2700049A03Rik
  • Rat genes LOC690035
  • Zfish genes si:ch211-185a18.2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set 2700049A03Rik

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	KIAA0586	IPI	UniProtKB:O43303	Human	PMID:24421332
Molecular Function	GO:0005515	protein binding	KIAA0586	IPI	UniProtKB:Q8TAP6	Human	PMID:24421332
Molecular Function	GO:0005515	protein binding	2700049A03Rik	IPI	UniProtKB:Q7TSG1	Mouse	MGI:MGI:5635753|PMID:25251415
Molecular Function	GO:0005515	protein binding	2700049A03Rik	IPI	UniProtKB:O43303	Mouse	PMID:24421332
Molecular Function	GO:0005515	protein binding	2700049A03Rik	IPI	UniProtKB:Q8IW35	Mouse	PMID:24421332
Molecular Function	GO:0005515	protein binding	2700049A03Rik	IPI	UniProtKB:O15078	Mouse	PMID:24421332
Molecular Function	GO:0005515	protein binding	2700049A03Rik	IPI	UniProtKB:P61006	Mouse	PMID:24421332
Molecular Function	GO:0005515	protein binding	2700049A03Rik	IPI	UniProtKB:Q5T7B8	Mouse	PMID:24421332
Molecular Function	GO:0005515	protein binding	2700049A03Rik	IPI	UniProtKB:Q15154	Mouse	PMID:24421332
Cellular Component	GO:0005814	centriole	si:ch211-185a18.2	IDA		Zfish	PMID:22028029|ZFIN:ZDB-PUB-111114-3
Cellular Component	GO:0005813	centrosome	KIAA0586	IDA		Human	PMID:19144723
Cellular Component	GO:0005813	centrosome	KIAA0586	IDA		Human	PMID:21399614
Cellular Component	GO:0005813	centrosome	KIAA0586	IDA		Human	PMID:24421332
Cellular Component	GO:0005813	centrosome	2700049A03Rik	IDA		Mouse	PMID:24421332
Cellular Component	GO:0036064	ciliary basal body	KIAA0586	IDA		Human	PMID:24421332
Cellular Component	GO:0036064	ciliary basal body	si:ch211-185a18.2	IDA		Zfish	PMID:22028029|ZFIN:ZDB-PUB-111114-3
Biological Process	GO:0060271	cilium assembly	KIAA0586	IMP		Human	PMID:24421332
Biological Process	GO:0060271	cilium assembly	2700049A03Rik	IMP		Mouse	MGI:MGI:5286003|PMID:21750036
Biological Process	GO:0060271	cilium assembly	si:ch211-185a18.2	IMP	ZFIN:ZDB-GENO-120120-3	Zfish	PMID:22028029
Biological Process	GO:0035845	photoreceptor cell outer segment organization	si:ch211-185a18.2	IMP	ZFIN:ZDB-GENO-180718-1	Zfish	PMID:29396404
Biological Process	GO:0070201	regulation of establishment of protein localization	KIAA0586	IMP		Human	PMID:24421332
Biological Process	GO:0007224	smoothened signaling pathway	2700049A03Rik	IMP		Mouse	MGI:MGI:5286003|PMID:21750036
Biological Process	GO:0007224	smoothened signaling pathway	si:ch211-185a18.2	IMP	ZFIN:ZDB-GENO-120120-3	Zfish	PMID:22028029

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern