Gene Expression Literature Summary

• Symbol: Plau
• Name: plasminogen activator, urokinase
• ID: MGI:97611

29 matching records from 29 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E1	E2	E3	E4	E5.5	E6.5	E7	E7.5	E8	E8.5	E9	E9.5	E10	E10.5	E11	E11.5	E12.5	E13.5	E14.5	E15.5	E16.5	E17	E17.5	E18.5	E19.5	E	P
Immunohistochemistry (section)										1														1			1
In situ RNA (section)					1	1	1	3	1	2	1	1		2	1	2	3	2	4	2	2	1	3	2	1		7
In situ RNA (whole mount)												1
In situ reporter (knock in)																											1
Northern blot												1		1		1	1	1	1	1	1	2	1	1	1		2
Western blot																			1			1					2
RT-PCR	1	1	1	1				1		1		5	1	2	1	2	2	3	2				1			1	4

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Plau  plasminogen activator, urokinase   (Synonyms: uPA, u-PA, urokinase-type plasminogen activator)
Results	Reference
1	J:139945 El-Bizri N, Guignabert C, Wang L, Cheng A, Stankunas K, Chang CP, Mishina Y, Rabinovitch M, SM22alpha-targeted deletion of bone morphogenetic protein receptor 1A in mice impairs cardiac and vascular development, and influences organogenesis. Development. 2008 Sep;135(17):2981-91
1	J:296619 Fan Y, Richelme S, Avazeri E, Audebert S, Helmbacher F, Dono R, Maina F, Tissue-Specific Gain of RTK Signalling Uncovers Selective Cell Vulnerability during Embryogenesis. PLoS Genet. 2015;11(9):e1005533
3*	J:29590 Friedman GC, Seeds NW, Tissue plasminogen activator mRNA expression in granule neurons coincides with their migration in the developing cerebellum. J Comp Neurol. 1995 Oct 2;360(4):658-70
4*	J:17731 Grevin D, Chen JH, Raes MB, Stehelin D, Vandenbunder B, Desbiens X, Involvement of the proto-oncogene c-ets 1 and the urokinase plasminogen activator during mouse implantation and placentation. Int J Dev Biol. 1993 Dec;37(4):519-29
2*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1*	J:231595 Gurdziel K, Vogt KR, Walton KD, Schneider GK, Gumucio DL, Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun. Dev Dyn. 2016 May;245(5):614-26
5*	J:24333 Harvey MB, Leco KJ, Arcellana-Panlilio MY, Zhang X, Edwards DR, Schultz GA, Proteinase expression in early mouse embryos is regulated by leukaemia inhibitory factor and epidermal growth factor. Development. 1995 APR;121(4):1005-14
1	J:250152 Hu X, Tang Z, Li Y, Liu W, Zhang S, Wang B, Tian Y, Zhao Y, Ran H, Liu W, Feng GS, Shuai J, Wang H, Lu Z, Deletion of the tyrosine phosphatase Shp2 in Sertoli cells causes infertility in mice. Sci Rep. 2015 Aug 12;5:12982
2	J:39694 Jensen PJ, Lavker RM, Modulation of the plasminogen activator cascade during enhanced epidermal proliferation in vivo. Cell Growth Differ. 1996 Dec;7(12):1793-804
1*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
1	J:184521 Koss M, Bolze A, Brendolan A, Saggese M, Capellini TD, Bojilova E, Boisson B, Prall OW, Elliott DA, Solloway M, Lenti E, Hidaka C, Chang CP, Mahlaoui N, Harvey RP, Casanova JL, Selleri L, Congenital Asplenia in Mice and Humans with Mutations in a Pbx/Nkx2-5/p15 Module. Dev Cell. 2012 May 15;22(5):913-26
2	J:272613 Koutelou E, Wang L, Schibler AC, Chao HP, Kuang X, Lin K, Lu Y, Shen J, Jeter CR, Salinger A, Wilson M, Chen YC, Atanassov BS, Tang DG, Dent SYR, USP22 controls multiple signaling pathways that are essential for vasculature formation in the mouse placenta. Development. 2019 Feb 22;146(4):dev174037
22*	J:24334 Lefebvre O, Regnier C, Chenard MP, Wendling C, Chambon P, Basset P, Rio MC, Developmental expression of mouse stromelysin-3 mRNA. Development. 1995 Apr;121(4):947-55
1	J:45195 Melnick M, Chen H, Buckley S, Warburton D, Jaskoll T, Insulin-like growth factor II receptor, transforming growth factor-beta, and Cdk4 expression and the developmental epigenetics of mouse palate morphogenesis and dysmorphogenesis. Dev Dyn. 1998 Jan;211(1):11-25
2	J:178271 Migliorini D, Bogaerts S, Defever D, Vyas R, Denecker G, Radaelli E, Zwolinska A, Depaepe V, Hochepied T, Skarnes WC, Marine JC, Cop1 constitutively regulates c-Jun protein stability and functions as a tumor suppressor in mice. J Clin Invest. 2011 Apr 1;121(4):1329-43
5	J:107650 Miskin R, Masos T, Shoham Z, Williams-Simons L, Urokinase-type Plasminogen Activator mRNA is Expressed in Normal Developing Teeth and Leads to Abnormal Incisor Enamel in alphaMUPA Transgenic Mice. Transgenic Res. 2006 Apr;15(2):241-54
5	J:88700 Odet F, Guyot R, Leduque P, Le Magueresse-Battistoni B, Evidence for similar expression of protein C inhibitor and the urokinase-type plasminogen activator system during mouse testis development. Endocrinology. 2004 Mar;145(3):1481-9
2	J:61177 Oh SP, Seki T, Goss KA, Imamura T, Yi Y, Donahoe PK, Li L, Miyazono K, ten Dijke P, Kim S, Li E, Activin receptor-like kinase 1 modulates transforming growth factor-beta 1 signaling in the regulation of angiogenesis. Proc Natl Acad Sci U S A. 2000 Mar 14;97(6):2626-31
9*	J:74089 Ong K, Horsfall W, Conway EM, Schuh AC, Early embryonic expression of murine coagulation system components. Thromb Haemost. 2000 Dec;84(6):1023-30
1	J:112269 Park C, Lavine K, Mishina Y, Deng CX, Ornitz DM, Choi K, Bone morphogenetic protein receptor 1A signaling is dispensable for hematopoietic development but essential for vessel and atrioventricular endocardial cushion formation. Development. 2006 Sep;133(17):3473-84
2*	J:29279 Patapoutian A, Yoon JK, Miner JH, Wang S, Stark K, Wold B, Disruption of the mouse MRF4 gene identifies multiple waves of myogenesis in the myotome. Development. 1995 Oct;121(10):3347-58
1	J:117504 Ponten A, Folestad EB, Pietras K, Eriksson U, Platelet-derived growth factor D induces cardiac fibrosis and proliferation of vascular smooth muscle cells in heart-specific transgenic mice. Circ Res. 2005 Nov 11;97(10):1036-45
1*	J:305712 Sanchez-Tillo E, de Barrios O, Siles L, Amendola PG, Darling DS, Cuatrecasas M, Castells A, Postigo A, ZEB1 Promotes invasiveness of colorectal carcinoma cells through the opposing regulation of uPA and PAI-1. Clin Cancer Res. 2013 Mar 1;19(5):1071-82
7*	J:33753 Teesalu T, Blasi F, Talarico D, Embryo implantation in mouse: fetomaternal coordination in the pattern of expression of uPA, uPAR, PAI-1 and alpha 2MR/LRP genes. Mech Dev. 1996 May;56(1-2):103-16
5	J:49265 Teesalu T, Blasi F, Talarico D, Expression and function of the urokinase type plasminogen activator during mouse hemochorial placental development. Dev Dyn. 1998 Sep;213(1):27-38
3*	J:53323 Teesalu T, Masson R, Basset P, Blasi F, Talarico D, Expression of matrix metalloproteinases during murine chorioallantoic placenta maturation. Dev Dyn. 1999 Mar;214(3):248-58
2*	J:17586 Timme TL, Truong LD, Merz VW, Krebs T, Kadmon D, Flanders KC, Park SH, Thompson TC, Mesenchymal-epithelial interactions and transforming growth factor-beta expression during mouse prostate morphogenesis. Endocrinology. 1994 Mar;134(3):1039-45
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
4	J:50541 Zhou HM, Nichols A, Wohlwend A, Bolon I, Vassalli JD, Extracellular proteolysis alters tooth development in transgenic mice expressing urokinase-type plasminogen activator in the enamel organ. Development. 1999 Feb;126(5):903-12