Gene Expression Literature Summary

• Symbol: Prl8a2
• Name: prolactin family 8, subfamily a, member 2
• ID: MGI:894281

18 matching records from 18 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E4.5	E5.5	E6.5	E7.5	E8	E8.5	E9	E9.5	E10	E10.5	E11.5	E12	E12.5	E13.5	E14	E14.5	E15.5	E16	E16.5	E17.5	E18	E18.5	E19.5	E	P
Immunohistochemistry (section)								1						1					1	1					4
In situ RNA (section)				2		2		1	1	2		1	1			2			1			1			6
Northern blot					1	1		1	1	1	1	1	1	2	1	1	1	1	2	1	1	1	1		3
Western blot																								1	2
RT-PCR	1	1	1			1				1	3									1					9
cDNA clones						1	1				1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Prl8a2  prolactin family 8, subfamily a, member 2   (Synonyms: DPRP, Dtprp, D/tPRP, mdPRP)
Results	Reference
2	J:93811 Ain R, Trinh ML, Soares MJ, Interleukin-11 signaling is required for the differentiation of natural killer cells at the maternal-fetal interface. Dev Dyn. 2004 Dec;231(4):700-8
2	J:278550 Boing M, Brand-Saberi B, Napirei M, Murine transcription factor Math6 is a regulator of placenta development. Sci Rep. 2018 Oct 9;8(1):14997
1	J:309444 Jiang Y, Kong S, He B, Wang B, Wang H, Lu J, Uterine Prx2 restrains decidual differentiation through inhibiting lipolysis in mice. Cell Tissue Res. 2016 Aug;365(2):403-14
1	J:240175 Kelleher AM, Peng W, Pru JK, Pru CA, DeMayo FJ, Spencer TE, Forkhead box a2 (FOXA2) is essential for uterine function and fertility. Proc Natl Acad Sci U S A. 2017 Feb 07;114(6):E1018-E1026
2	J:305960 Li F, Xu R, Lin CL, Low BE, Cai L, Li S, Ji P, Huang L, Wiles MV, Hannun YA, Obeid LM, Chen Y, Mao C, Maternal and fetal alkaline ceramidase 2 is required for placental vascular integrity in mice. FASEB J. 2020 Nov;34(11):15252-15268
10*	J:44453 Lin J, Poole J, Linzer DI, Three new members of the mouse prolactin/growth hormone family are homologous to proteins expressed in the rat. Endocrinology. 1997 Dec;138(12):5541-9
3	J:322043 Liu M, Deng W, Tang L, Liu M, Bao H, Guo C, Zhang C, Lu J, Wang H, Lu Z, Kong S, Menin directs regionalized decidual transformation through epigenetically setting PTX3 to balance FGF and BMP signaling. Nat Commun. 2022 Feb 22;13(1):1006
3	J:171849 Mori M, Kitazume M, Ose R, Kurokawa J, Koga K, Osuga Y, Arai S, Miyazaki T, Death effector domain-containing protein (DEDD) is required for uterine decidualization during early pregnancy in mice. J Clin Invest. 2011 Jan 4;121(1):318-27
2	J:201437 Nagashima T, Li Q, Clementi C, Lydon JP, DeMayo FJ, Matzuk MM, BMPR2 is required for postimplantation uterine function and pregnancy maintenance. J Clin Invest. 2013 Jun 3;123(6):2539-50
13	J:42315 Orwig KE, Ishimura R, Muller H, Liu B, Soares MJ, Identification and characterization of a mouse homolog for decidual/trophoblast prolactin-related protein. Endocrinology. 1997 Dec;138(12):5511-7
1	J:74745 Pfisterer P, Ehlermann J, Hegen M, Schorle H, A subtractive gene expression screen suggests a role of transcription factor AP-2 alpha in control of proliferation and differentiation. J Biol Chem. 2002 Feb 22;277(8):6637-44
3*	J:225719 Rakoczy J, Lee S, Weerasekera SJ, Simmons DG, Dawson PA, Placental and fetal cysteine dioxygenase gene expression in mouse gestation. Placenta. 2015 Aug;36(8):956-9
21*	J:139954 Simmons DG, Rawn S, Davies A, Hughes M, Cross JC, Spatial and temporal expression of the 23 murine Prolactin/Placental Lactogen-related genes is not associated with their position in the locus. BMC Genomics. 2008;9:352
4*	J:116679 Singh U, Yu Y, Kalinina E, Konno T, Sun T, Ohta H, Wakayama T, Soares MJ, Hemberger M, Fundele RH, Carboxypeptidase E in the mouse placenta. Differentiation. 2006 Dec;74(9-10):648-60
2	J:337679 Sirohi VK, Medrano TI, Kannan A, Bagchi IC, Cooke PS, Uterine-specific Ezh2 deletion enhances stromal cell senescence and impairs placentation, resulting in pregnancy loss. iScience. 2023 Jul 21;26(7):107028
2*	J:147173 Sultana DA, Tomita S, Hamada M, Iwanaga Y, Kitahama Y, Khang NV, Hirai S, Ohigashi I, Nitta S, Amagai T, Takahashi S, Takahama Y, Gene expression profile of the third pharyngeal pouch reveals role of mesenchymal MafB in embryonic thymus development. Blood. 2009 Mar 26;113(13):2976-87
1	J:324161 Tang S, Cope DI, Vasquez YM, Monsivais D, BMP/SMAD1/5 Signaling in the Endometrial Epithelium Is Essential for Receptivity and Early Pregnancy. Endocrinology. 2022 May 1;163(5)
2	J:315981 Torregrosa-Carrion R, Pineiro-Sabaris R, Siguero-Alvarez M, Grego-Bessa J, Luna-Zurita L, Fernandes VS, MacGrogan D, Stainier DYR, de la Pompa JL, Adhesion G protein-coupled receptor Gpr126/Adgrg6 is essential for placental development. Sci Adv. 2021 Nov 12;7(46):eabj5445