Gene Expression Literature Summary

• Symbol: Chrna4
• Name: cholinergic receptor, nicotinic, alpha polypeptide 4
• ID: MGI:87888

14 matching records from 14 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E11.5	E12	E13	E13.5	E14	E14.5	E15	E15.5	E16	E17	E17.5	E18	E18.5	E	P
Immunohistochemistry (section)													1
In situ RNA (section)	1	1		1		4		2	2				2	1	4
In situ RNA (whole mount)								1
Northern blot	1			1				1			1				1
RT-PCR	1	1	1		1	1	1		1	1	1	1			3
RNase protection									1						1
Primer Extension															1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Chrna4  cholinergic receptor, nicotinic, alpha polypeptide 4   (Synonyms: a4 nicotinic receptor, Acra4, Acra-4, alpha4 nAChR, alpha4-nAChR)
Results	Reference
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
1	J:334607 Bsharat S, Monni E, Singh T, Johansson JK, Achanta K, Bertonnier-Brouty L, Schmidt-Christensen A, Holmberg D, Kokaia Z, Prasad RB, Artner I, MafB-dependent neurotransmitter signaling promotes beta cell migration in the developing pancreas. Development. 2023 Mar 15;150(6):dev201009
1	J:186385 Chakrabarty K, Von Oerthel L, Hellemons A, Clotman F, Espana A, Koerkamp MG, Holstege FC, Pasterkamp RJ, Smidt MP, Genome wide expression profiling of the mesodiencephalic region identifies novel factors involved in early and late dopaminergic development. Biol Open. 2012;1:693-704
2	J:31245 Didier M, Bix G, Berman SA, Bursztajn S, Expression of the alpha 4 neuronal nicotinic acetylcholine receptor subunit in the developing mouse hippocampus. Int J Dev Neurosci. 1995 Nov;13(7):703-13
3*	J:221646 Foong JP, Hirst CS, Hao MM, McKeown SJ, Boesmans W, Young HM, Bornstein JC, Vanden Berghe P, Changes in Nicotinic Neurotransmission during Enteric Nervous System Development. J Neurosci. 2015 May 6;35(18):7106-15
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
3*	J:195324 Hoerder-Suabedissen A, Oeschger FM, Krishnan ML, Belgard TG, Wang WZ, Lee S, Webber C, Petretto E, Edwards AD, Molnar Z, Expression profiling of mouse subplate reveals a dynamic gene network and disease association with autism and schizophrenia. Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3555-60
8*	J:80959 Kuo Y, Lucero L, Michaels J, DeLuca D, Lukas RJ, Differential expression of nicotinic acetylcholine receptor subunits in fetal and neonatal mouse thymus. J Neuroimmunol. 2002 Sep;130(1-2):140-54
5*	J:55981 O'Hara BF, Macdonald E, Clegg D, Wiler SW, Andretic R, Cao VH, Miller JD, Heller HC, Kilduff TS, Developmental changes in nicotinic receptor mRNAs and responses to nicotine in the suprachiasmatic nucleus and other brain regions. Brain Res Mol Brain Res. 1999 Mar 20;66(1-2):71-82
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1*	J:127119 Visel A, Carson J, Oldekamp J, Warnecke M, Jakubcakova V, Zhou X, Shaw CA, Alvarez-Bolado G, Eichele G, Regulatory pathway analysis by high-throughput in situ hybridization. PLoS Genet. 2007 Oct 19;3(10):1867-83
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
7	J:61932 Watanabe H, Zoli M, Changeux JP, Promoter analysis of the neuronal nicotinic acetylcholine receptor alpha4 gene: methylation and expression of the transgene. Eur J Neurosci. 1998 Jul;10(7):2244-53
2	J:25759 Williamson CM, Dutton ER, Abbott CM, Beechey CV, Ball ST, Peters J, Thirteen genes (Cebpb, E2f1, Tcf4, Cyp24, Pck1, Acra4, Edn3, Kcnb1, Mc3r, Ntsr, Cd40, Plcg1 and Rcad) that probably lie in the distal imprinting region of mouse chromosome 2 are not monoallelically expressed. Genet Res. 1995 Apr;65(2):83-93