Symbol Name ID |
Piezo1
piezo-type mechanosensitive ion channel component 1 MGI:3603204 |
Age | E9 | E9.5 | E10.5 | E11.5 | E12.5 | E13.5 | E14 | E14.5 | E15 | E15.5 | E16 | E16.5 | E | P |
Immunohistochemistry (section) | 1 | 1 | 1 | |||||||||||
In situ RNA (section) | 1 | 1 | ||||||||||||
In situ RNA (whole mount) | 1 | 1 | 1 | 1 | ||||||||||
In situ reporter (knock in) | 1 | 1 | 1 | 1 | 1 | |||||||||
Western blot | 2 | |||||||||||||
RT-PCR | 1 | 1 | 1 | 1 | 1 | 1 | 3 |
Piezo1 piezo-type mechanosensitive ion channel component 1 (Synonyms: Fam38a, Piezo1) | |
Results | Reference |
6* | J:197533 Andolfo I, Alper SL, De Franceschi L, Auriemma C, Russo R, De Falco L, Vallefuoco F, Esposito MR, Vandorpe DH, Shmukler BE, Narayan R, Montanaro D, D'Armiento M, Vetro A, Limongelli I, Zuffardi O, Glader BE, Schrier SL, Brugnara C, Stewart GW, Delaunay J, Iolascon A, Multiple clinical forms of dehydrated hereditary stomatocytosis arise from mutations in PIEZO1. Blood. 2013 May 9;121(19):3925-35, S1-12 |
2 | J:217082 Li J, Hou B, Tumova S, Muraki K, Bruns A, Ludlow MJ, Sedo A, Hyman AJ, McKeown L, Young RS, Yuldasheva NY, Majeed Y, Wilson LA, Rode B, Bailey MA, Kim HR, Fu Z, Carter DA, Bilton J, Imrie H, Ajuh P, Dear TN, Cubbon RM, Kearney MT, Prasad KR, Evans PC, Ainscough JF, Beech DJ, Piezo1 integration of vascular architecture with physiological force. Nature. 2014 Nov 13;515(7526):279-82 |
1* | J:333869 Nourse JL, Leung VM, Abuwarda H, Evans EL, Izquierdo-Ortiz E, Ly AT, Truong N, Smith S, Bhavsar H, Bertaccini G, Monuki ES, Panicker MM, Pathak MM, Piezo1 regulates cholesterol biosynthesis to influence neural stem cell fate during brain development. J Gen Physiol. 2022 Oct 3;154(10) |
4 | J:334608 Pokharel E, Aryal YP, Kim TY, Kim A, Kim JY, Yamamoto H, Cho SW, Sohn WJ, Kim JY, Jung JK, Developmental function of Piezo1 in mouse submandibular gland morphogenesis. Histochem Cell Biol. 2023 Feb 22; |
6 | J:212179 Ranade SS, Qiu Z, Woo SH, Hur SS, Murthy SE, Cahalan SM, Xu J, Mathur J, Bandell M, Coste B, Li YS, Chien S, Patapoutian A, Piezo1, a mechanically activated ion channel, is required for vascular development in mice. Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10347-52 |
6 | J:292430 Zhou T, Gao B, Fan Y, Liu Y, Feng S, Cong Q, Zhang X, Zhou Y, Yadav PS, Lin J, Wu N, Zhao L, Huang D, Zhou S, Su P, Yang Y, Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ss-catenin. Elife. 2020 Mar 18;9:e52779 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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