Gene Expression Literature Summary

• Symbol: Magel2
• Name: MAGE family member L2
• ID: MGI:1351648

32 matching records from 32 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E6.5	E7	E7.5	E8.5	E9.5	E10	E10.5	E11	E11.5	E12	E12.5	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E18	E18.5	E19	E19.5	E	P
In situ RNA (section)							2		2		5			6		2	1	2			3				2
In situ RNA (whole mount)				1			2				2
In situ reporter (knock in)																		1						1	2
Northern blot		1				1		1		1			1		1		1		1	1		1		1	3
RT-PCR	1		2		2		5					2		8		1		1					5		11
cDNA clones							1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Magel2  MAGE family member L2   (Synonyms: Mage-l2, NDNL1, nM15, ns7)
Results	Reference
1*	J:100830 Bischof JM, Wevrick R, Genome-wide analysis of gene transcription in the hypothalamus. Physiol Genomics. 2005 Jul 14;22(2):191-6
3*	J:58785 Boccaccio I, Glatt-Deeley H, Watrin F, Roeckel N, Lalande M, Muscatelli F, The human MAGEL2 gene and its mouse homologue are paternally expressed and mapped to the Prader-Willi region. Hum Mol Genet. 1999 Dec;8(13):2497-505
3	J:174459 Boyle MP, Bernard A, Thompson CL, Ng L, Boe A, Mortrud M, Hawrylycz MJ, Jones AR, Hevner RF, Lein ES, Cell-type-specific consequences of Reelin deficiency in the mouse neocortex, hippocampus, and amygdala. J Comp Neurol. 2011 Aug 1;519(11):2061-89
1	J:153556 Colasante G, Sessa A, Crispi S, Calogero R, Mansouri A, Collombat P, Broccoli V, Arx acts as a regional key selector gene in the ventral telencephalon mainly through its transcriptional repression activity. Dev Biol. 2009 Oct 1;334(1):59-71
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
3*	J:138839 Fulp CT, Cho G, Marsh ED, Nasrallah IM, Labosky PA, Golden JA, Identification of Arx transcriptional targets in the developing basal forebrain. Hum Mol Genet. 2008;17(23):3740-60
1	J:204566 Gendrel AV, Tang YA, Suzuki M, Godwin J, Nesterova TB, Greally JM, Heard E, Brockdorff N, Epigenetic functions of smchd1 repress gene clusters on the inactive X chromosome and on autosomes. Mol Cell Biol. 2013 Aug;33(16):3150-65
1*	J:230330 Gordeeva O, Expression of the genes of the melanoma antigen (Mage) families in E7.5 mouse embryo. MGI Direct Data Submission. 2016;
4*	J:237181 Gordeeva O, Expression of the genes of the melanoma antigen (Mage) families in placenta. MGI Direct Data Submission. 2016;
3*	J:255000 Gordeeva O, Expression of the genes of the melanoma antigen (Mage) families in brain. MGI Direct Data Submission. 2018;
3*	J:257298 Gordeeva O, Expression of the genes of the melanoma antigen (Mage) families in heart. MGI Direct Data Submission. 2018;
3*	J:257299 Gordeeva O, Expression of the genes of the melanoma antigen (Mage) families in liver. MGI Direct Data Submission. 2018;
1*	J:260954 Gordeeva O, Expression Patterns of Cancer-Testis Antigens of Mage Families in Somatic and Reproductive Organs of Immunocompetent and Immunodeficient Mice. MGI Direct Data Submission. 2018;
3*	J:262143 Gordeeva O, Expression of the genes of the melanoma antigen (Mage) families in male and female gonad. MGI Direct Data Submission. 2018;
2	J:310310 Gordeeva O, Gordeev A, Khaydukov S, Expression dynamics of Mage family genes during self-renewal and differentiation of mouse pluripotent stem and teratocarcinoma cells. Oncotarget. 2019 May 14;10(35):3248-3266
1*	J:256265 Gordeeva OF, Pochaev VA, Expression of Cancer-Testis Antigens of the Mage Family in Mouse Oocytes and Early Embryos. Russ J Dev Biol. 2017;48(4):287-294
5	J:233299 Kamaludin AA, Smolarchuk C, Bischof JM, Eggert R, Greer JJ, Ren J, Lee JJ, Yokota T, Berry FB, Wevrick R, Muscle dysfunction caused by loss of Magel2 in a mouse model of Prader-Willi and Schaaf-Yang syndromes. Hum Mol Genet. 2016 Sep 1;25(17):3798-3809
5	J:125637 Kozlov SV, Bogenpohl JW, Howell MP, Wevrick R, Panda S, Hogenesch JB, Muglia LJ, Van Gelder RN, Herzog ED, Stewart CL, The imprinted gene Magel2 regulates normal circadian output. Nat Genet. 2007 Oct;39(10):1266-72
6	J:315293 Kumamoto T, Toma K, Gunadi, McKenna WL, Kasukawa T, Katzman S, Chen B, Hanashima C, Foxg1 coordinates the switch from nonradially to radially migrating glutamatergic subtypes in the neocortex through spatiotemporal repression. Cell Rep. 2013 Mar 28;3(3):931-45
6*	J:87556 Kuwako K, Taniura H, Yoshikawa K, Necdin-related MAGE proteins differentially interact with the E2F1 transcription factor and the p75 neurotrophin receptor. J Biol Chem. 2004 Jan 16;279(3):1703-12
10*	J:63703 Lee S, Kozlov S, Hernandez L, Chamberlain SJ, Brannan CI, Stewart CL, Wevrick R, Expression and imprinting of MAGEL2 suggest a role in Prader-willi syndrome and the homologous murine imprinting phenotype. Hum Mol Genet. 2000 Jul 22;9(12):1813-9
1*	J:96395 Lee S, Walker CL, Karten B, Kuny SL, Tennese AA, O'Neill MA, Wevrick R, Essential role for the Prader-Willi syndrome protein necdin in axonal outgrowth. Hum Mol Genet. 2005 Mar 1;14(5):627-37
6	J:85656 Lee S, Walker CL, Wevrick R, Prader-Willi syndrome transcripts are expressed in phenotypically significant regions of the developing mouse brain. Gene Expr Patterns. 2003 Oct;3(5):599-609
1*	J:143569 Miller NL, Wevrick R, Mellon PL, Necdin, a Prader-Willi syndrome candidate gene, regulates gonadotropin-releasing hormone neurons during development. Hum Mol Genet. 2009 Jan 15;18(2):248-60
1	J:217174 Nakagaki A, Osanai H, Kishino T, Imprinting analysis of the mouse chromosome 7C region in DNMT1-null embryos. Gene. 2014 Dec 10;553(1):63-8
1	J:112969 Ogawa H, Wu Q, Komiyama J, Obata Y, Kono T, Disruption of parental-specific expression of imprinted genes in uniparental fetuses. FEBS Lett. 2006 Oct 2;580(22):5377-84
1*	J:166548 Schaller F, Watrin F, Sturny R, Massacrier A, Szepetowski P, Muscatelli F, A single postnatal injection of oxytocin rescues the lethal feeding behaviour in mouse newborns deficient for the imprinted Magel2 gene. Hum Mol Genet. 2010 Dec 15;19(24):4895-905
1	J:136953 Shaut CA, Keene DR, Sorensen LK, Li DY, Stadler HS, HOXA13 Is essential for placental vascular patterning and labyrinth endothelial specification. PLoS Genet. 2008 May;4(5):e1000073
4*	J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75
1*	J:152022 Skryabin BV, Gubar LV, Seeger B, Pfeiffer J, Handel S, Robeck T, Karpova E, Rozhdestvensky TS, Brosius J, Deletion of the MBII-85 snoRNA gene cluster in mice results in postnatal growth retardation. PLoS Genet. 2007 Dec 28;3(12):e235
1	J:172308 Stefan M, Simmons RA, Bertera S, Trucco M, Esni F, Drain P, Nicholls RD, Global deficits in development, function, and gene expression in the endocrine pancreas in a deletion mouse model of Prader-Willi syndrome. Am J Physiol Endocrinol Metab. 2011 May;300(5):E909-22
3	J:101829 Watrin F, Le Meur E, Roeckel N, Ripoche MA, Dandolo L, Muscatelli F, The Prader-Willi syndrome murine imprinting center is not involved in the spatio-temporal transcriptional regulation of the Necdin gene. BMC Genet. 2005 Jan 5;6(1):1