Gene Expression Literature Summary

• Symbol: Ppp1r12a
• Name: protein phosphatase 1, regulatory subunit 12A
• ID: MGI:1309528

16 matching records from 16 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E8	E8.5	E9.5	E10	E10.5	E12.5	E13	E14	E14.5	E15	E16.5	E17	E17.5	E	P
Immunohistochemistry (section)				1	1		1	1				1		1
In situ RNA (section)		1
In situ RNA (whole mount)		1
In situ reporter (knock in)								1							1
Western blot	1		3			2			1	1	1		1		2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Ppp1r12a  protein phosphatase 1, regulatory subunit 12A   (Synonyms: 1200015F06Rik, 5730577I22Rik, D10Ertd625e, Mypt1)
Results	Reference
1	J:228507 Ajima R, Bisson JA, Helt JC, Nakaya MA, Habas R, Tessarollo L, He X, Morrisey EE, Yamaguchi TP, Cohen ED, DAAM1 and DAAM2 are co-required for myocardial maturation and sarcomere assembly. Dev Biol. 2015 Dec 1;408(1):126-39
1*	J:305526 Awazu M, Yamaguchi Y, Nagata M, Miura M, Hida M, Caspase-3 regulates ureteric branching in mice via cell migration. Biochem Biophys Res Commun. 2021 Apr 28;559:28-34
1	J:266546 Brown JM, Garcia-Garcia MJ, Secretory pathway calcium ATPase 1 (SPCA1) controls mouse neural tube closure by regulating cytoskeletal dynamics. Development. 2018 Oct 5;145(19):dev170019
2*	J:293794 Durbin MD, O'Kane J, Lorentz S, Firulli AB, Ware SM, SHROOM3 is downstream of the planar cell polarity pathway and loss-of-function results in congenital heart defects. Dev Biol. 2020 Aug 15;464(2):124-136
1*	J:303862 Hada K, Wulaer B, Nagai T, Itoh N, Sawahata M, Sobue A, Mizoguchi H, Mori D, Kushima I, Nabeshima T, Ozaki N, Yamada K, Mice carrying a schizophrenia-associated mutation of the Arhgap10 gene are vulnerable to the effects of methamphetamine treatment on cognitive function: association with morphological abnormalities in striatal neurons. Mol Brain. 2021 Jan 22;14(1):21
1	J:314852 Hu W, Dong A, Karasaki K, Sogabe S, Okamoto D, Saigo M, Ishida M, Yoshizumi M, Kokubo H, Smad4 regulates the nuclear translocation of Nkx2-5 in cardiac differentiation. Sci Rep. 2021 Feb 11;11(1):3588
4*	J:296646 Hughes JJ, Alkhunaizi E, Kruszka P, Pyle LC, Grange DK, Berger SI, Payne KK, Masser-Frye D, Hu T, Christie MR, Clegg NJ, Everson JL, Martinez AF, Walsh LE, Bedoukian E, Jones MC, Harris CJ, Riedhammer KM, Choukair D, Fechner PY, Rutter MM, Hufnagel SB, Roifman M, Kletter GB, Delot E, Vilain E, Lipinski RJ, Vezina CM, Muenke M, Chitayat D, Loss-of-Function Variants in PPP1R12A: From Isolated Sex Reversal to Holoprosencephaly Spectrum and Urogenital Malformations. Am J Hum Genet. 2020 Jan 2;106(1):121-128
1	J:189368 Kamijo H, Matsumura Y, Thumkeo D, Koike S, Masu M, Shimizu Y, Ishizaki T, Narumiya S, Impaired vascular remodeling in the yolk sac of embryos deficient in ROCK-I and ROCK-II. Genes Cells. 2011 Oct;16(10):1012-21
2*	J:151682 Kim JI, Young GD, Jin L, Somlyo AV, Eto M, Expression of CPI-17 in smooth muscle during embryonic development and in neointimal lesion formation. Histochem Cell Biol. 2009 Aug;132(2):191-8
1	J:100207 Kobayashi K, Takahashi M, Matsushita N, Miyazaki J, Koike M, Yaginuma H, Osumi N, Kaibuchi K, Kobayashi K, Survival of developing motor neurons mediated by Rho GTPase signaling pathway through Rho-kinase. J Neurosci. 2004 Apr 7;24(14):3480-8
1	J:167714 Li D, Hallett MA, Zhu W, Rubart M, Liu Y, Yang Z, Chen H, Haneline LS, Chan RJ, Schwartz RJ, Field LJ, Atkinson SJ, Shou W, Dishevelled-associated activator of morphogenesis 1 (Daam1) is required for heart morphogenesis. Development. 2011 Jan;138(2):303-15
1	J:169135 Mao Y, Mulvaney J, Zakaria S, Yu T, Morgan KM, Allen S, Basson MA, Francis-West P, Irvine KD, Characterization of a Dchs1 mutant mouse reveals requirements for Dchs1-Fat4 signaling during mammalian development. Development. 2011 Mar;138(5):947-57
1	J:333966 Nagaoka T, Katsuno T, Fujimura K, Tsuchida K, Kishi M, Functional interaction between Vangl2 and N-cadherin regulates planar cell polarization of the developing neural tube and cochlear sensory epithelium. Sci Rep. 2023 Mar 8;13(1):3905
2	J:322229 Oslin K, Reho JJ, Lu Y, Khanal S, Kenchegowda D, Prior SJ, Fisher SA, Tissue-specific expression of myosin phosphatase subunits and isoforms in smooth muscle of mice and humans. Am J Physiol Regul Integr Comp Physiol. 2022 Apr 1;322(4):R281-R291
1	J:152701 Suriben R, Kivimae S, Fisher DA, Moon RT, Cheyette BN, Posterior malformations in Dact1 mutant mice arise through misregulated Vangl2 at the primitive streak. Nat Genet. 2009 Sep;41(9):977-85
1	J:176219 Yamauchi J, Miyamoto Y, Hamasaki H, Sanbe A, Kusakawa S, Nakamura A, Tsumura H, Maeda M, Nemoto N, Kawahara K, Torii T, Tanoue A, The atypical Guanine-nucleotide exchange factor, dock7, negatively regulates schwann cell differentiation and myelination. J Neurosci. 2011 Aug 31;31(35):12579-92