Gene Expression Literature Summary

• Symbol: Gclm
• Name: glutamate-cysteine ligase, modifier subunit
• ID: MGI:104995

11 matching records from 11 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7.5	E10	E10.5	E12	E12.5	E13.5	E14	E14.5	E15.5	E16	E16.5	E18.5	E	P
In situ RNA (section)		1	1	1	1		1	3		1	1	1		1
Western blot											1
RT-PCR	1		1		1	1		1	2		1	3	1	4

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Gclm  glutamate-cysteine ligase, modifier subunit   (Synonyms: Gcmc, Glclr)
Results	Reference
1*	J:124356 Bondareva AA, Capecchi MR, Iverson SV, Li Y, Lopez NI, Lucas O, Merrill GF, Prigge JR, Siders AM, Wakamiya M, Wallin SL, Schmidt EE, Effects of thioredoxin reductase-1 deletion on embryogenesis and transcriptome. Free Radic Biol Med. 2007 Sep 15;43(6):911-23
3	J:314222 Celaya AM, Rodriguez-de la Rosa L, Bermudez-Munoz JM, Zubeldia JM, Roma-Mateo C, Avendano C, Pallardo FV, Varela-Nieto I, IGF-1 Haploinsufficiency Causes Age-Related Chronic Cochlear Inflammation and Increases Noise-Induced Hearing Loss. Cells. 2021 Jul 3;10(7)
1	J:274697 Celaya AM, Sanchez-Perez I, Bermudez-Munoz JM, Rodriguez-de la Rosa L, Pintado-Berninches L, Perona R, Murillo-Cuesta S, Varela-Nieto I, Deficit of mitogen-activated protein kinase phosphatase 1 (DUSP1) accelerates progressive hearing loss. Elife. 2019 Apr 2;8:e39159
4*	J:75783 Diaz D, Krejsa CM, Kavanagh TJ, Expression of glutamate-cysteine ligase during mouse development. Mol Reprod Dev. 2002 May;62(1):83-91
12	J:93103 Diaz D, Krejsa CM, White CC, Charleston JS, Kavanagh TJ, Effect of methylmercury on glutamate-cysteine ligase expression in the placenta and yolk sac during mouse development. Reprod Toxicol. 2004 Nov;19(1):117-29
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1	J:175212 Meixner A, Karreth F, Kenner L, Penninger JM, Wagner EF, Jun and JunD-dependent functions in cell proliferation and stress response. Cell Death Differ. 2010 Sep;17(9):1409-19
3*	J:287221 Partearroyo T, Murillo-Cuesta S, Vallecillo N, Bermudez-Munoz JM, Rodriguez-de la Rosa L, Mandruzzato G, Celaya AM, Zeisel SH, Pajares MA, Varela-Moreiras G, Varela-Nieto I, Betaine-homocysteine S-methyltransferase deficiency causes increased susceptibility to noise-induced hearing loss associated with plasma hyperhomocysteinemia. FASEB J. 2019 May;33(5):5942-5956
1*	J:74071 Thompson SA, White CC, Krejsa CM, Eaton DL, Kavanagh TJ, Modulation of glutathione and glutamate-L-cysteine ligase by methylmercury during mouse development. Toxicol Sci. 2000 Sep;57(1):141-6
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
1	J:318865 Zheng B, Zhao D, Zhang P, Shen C, Guo Y, Zhou T, Guo X, Zhou Z, Sha J, Quantitative Proteomics Reveals the Essential Roles of Stromal Interaction Molecule 1 (STIM1) in the Testicular Cord Formation in Mouse Testis. Mol Cell Proteomics. 2015 Oct;14(10):2682-91