Automated description from the Alliance of Genome Resources (Release 8.3.0)
Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; enzyme binding activity; and phosphatidylinositol 3-kinase regulatory subunit binding activity. Involved in several processes, including cellular response to hexose stimulus; intracellular signal transduction; and regulation of gene expression. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; exocrine system development; and positive regulation of macromolecule metabolic process. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; sensory organ; and skeletal system. Used to study inflammatory bowel disease. Orthologous to human XBP1 (X-box binding protein 1).
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