Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable several functions, including DNA binding activity; DNA clamp unloader activity; and DNA-binding transcription factor binding activity. Predicted to be involved in DNA-templated DNA replication; negative regulation of transcription by RNA polymerase II; and positive regulation of DNA-templated transcription. Located in nucleus. Is expressed in several structures, including adrenal gland; alimentary system; central nervous system; genitourinary system; and retina. Human ortholog(s) of this gene implicated in West Nile fever and congenital heart disease. Orthologous to human RFC1 (replication factor C subunit 1).