Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables glutamate receptor binding activity; phosphatidylinositol phospholipase C activity; and receptor tyrosine kinase binding activity. Involved in modulation of chemical synaptic transmission. Acts upstream of or within T cell receptor signaling pathway and in utero embryonic development. Located in cell-cell junction. Is active in Schaffer collateral - CA1 synapse and glutamatergic synapse. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and integumental system. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and lung non-small cell carcinoma. Orthologous to human PLCG1 (phospholipase C gamma 1).