Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 9.0.0)

Enables brain-derived neurotrophic factor binding activity and brain-derived neurotrophic factor receptor activity. Involved in several processes, including modulation of chemical synaptic transmission; negative regulation of anoikis; and nervous system development. Acts upstream of or within several processes, including neurogenesis; neuronal action potential propagation; and positive regulation of peptidyl-serine phosphorylation. Located in several cellular components, including early endosome; postsynaptic density; and postsynaptic membrane. Is expressed in several structures, including alimentary system; genitourinary system; head mesenchyme; integumental system; and nervous system. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; autistic disorder; developmental and epileptic encephalopathy 58; heroin dependence; and morbid obesity. Orthologous to human NTRK2 (neurotrophic receptor tyrosine kinase 2).

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Gene Ontology Evidence Code Abbreviations:

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