Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 9.0.0)

Enables cytokine activity and interleukin-2 receptor binding activity. Involved in negative regulation of T-helper 17 cell differentiation. Acts upstream of or within several processes, including extrinsic apoptotic signaling pathway in absence of ligand; regulation of gene expression; and regulation of lymphocyte activation. Located in extracellular region. Is expressed in liver; omental bursa; thymus; and thymus primordium. Used to study Sjogren's syndrome and inflammatory bowel disease. Human ortholog(s) of this gene implicated in several diseases, including auditory system disease (multiple); autoimmune disease of musculoskeletal system (multiple); carcinoma (multiple); neurodegenerative disease (multiple); and primary immunodeficiency disease (multiple). Orthologous to human IL2 (interleukin 2).

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Gene Ontology Evidence Code Abbreviations:

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