Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables several functions, including identical protein binding activity; nuclear glucocorticoid receptor activity; and protein kinase binding activity. Involved in several processes, including glial cell differentiation; glucocorticoid receptor signaling pathway; and positive regulation of miRNA transcription. Acts upstream of or within several processes, including maternal behavior; regulation of glucocorticoid biosynthetic process; and regulation of gluconeogenesis. Located in cytosol; membrane; and nucleus. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and leg muscle. Used to study primary hyperaldosteronism. Human ortholog(s) of this gene implicated in several diseases, including anorexia nervosa; lung disease (multiple); major depressive disorder; obesity; and renal cell carcinoma. Orthologous to human NR3C1 (nuclear receptor subfamily 3 group C member 1).