Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable several functions, including alpha-tubulin binding activity; beta-catenin binding activity; and gap junction channel activity. Predicted to be involved in cell communication by electrical coupling; cell-cell signaling; and heart development. Predicted to be located in several cellular components, including gap junction; intercalated disc; and tight junction. Predicted to be part of connexin complex. Is expressed in embryo. Human ortholog(s) of this gene implicated in several diseases, including bone disease (multiple); erythrokeratodermia variabilis (multiple); hypoplastic left heart syndrome; oculodentodigital dysplasia; and palmoplantar keratoderma and congenital alopecia 1. Orthologous to several human genes including GJA1 (gap junction protein alpha 1).