Automated description from the Alliance of Genome Resources (Release 6.0.0)
Enables corticotrophin-releasing factor receptor activity and hormone activity. Acts upstream of or within G protein-coupled receptor signaling pathway; cellular response to corticotropin-releasing hormone stimulus; and negative regulation of angiogenesis. Predicted to be located in cell body fiber; perikaryon; and varicosity. Predicted to be active in axon terminus; dendrite; and plasma membrane. Is expressed in several structures, including brain; genitourinary system; gut; hemolymphoid system gland; and integumental system. Human ortholog(s) of this gene implicated in asthma. Orthologous to human CRHR2 (corticotropin releasing hormone receptor 2).