Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables identical protein binding activity and mechanosensitive monoatomic cation channel activity. Involved in monoatomic cation transport and positive regulation of myotube differentiation. Acts upstream of or within detection of mechanical stimulus; monoatomic cation transmembrane transport; and regulation of membrane potential. Located in plasma membrane. Is expressed in several structures, including brain; hemolymphoid system; liver; and lung. Human ortholog(s) of this gene implicated in dehydrated hereditary stomatocytosis 1 and hereditary lymphedema. Orthologous to human PIEZO1 (piezo type mechanosensitive ion channel component 1 (Er blood group)).