Automated description from the Alliance of Genome Resources (Release 7.1.0)
Acts upstream of or within several processes, including cilium assembly; determination of left/right symmetry; and single fertilization. Is active in cytosol and sperm flagellum. Is expressed in several structures, including brain; nasal cavity respiratory epithelium; and respiratory system epithelium. Used to study Kartagener syndrome; primary ciliary dyskinesia 21; and visceral heterotaxy. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 21 and spermatogenic failure. Orthologous to human DRC1 (dynein regulatory complex subunit 1).