Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables G protein-coupled receptor activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning. Located in several cellular components, including cilium; glial cell projection; and recycling endosome. Is expressed in several structures, including central nervous system; eye; and limb. Human ortholog(s) of this gene implicated in medulloblastoma. Orthologous to human GPR161 (G protein-coupled receptor 161).